SCHEMBL673676

SCHEMBL673676

O=C(O)CC(Cc1ccccc1)(OCc1ccccc1)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
TDP1 Q9NUW8 2/20 0.43
SLC6A2 P23975 1/20 0.43
SLC6A3 Q01959 1/20 0.43
KMT2A Q03164 1/20 0.43
PTPN1 P18031 1/20 0.41
ALDH1A1 P00352 4/20 0.41
LMNA P02545 1/20 0.40
TSHR P16473 2/20 0.40
MAPK1 P28482 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
HTT P42858 1/20 0.39
AKR1B1 P15121 1/20 0.38
FFAR1 O14842 1/20 0.37
FFAR4 Q5NUL3 1/20 0.37
POLB P06746 1/20 0.37
PPARG P37231 1/20 0.37
PPARA Q07869 1/20 0.37
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11169158 0.87 TDP1 (0.41) HIF1ASMN1; SMN2TDP1SLC6A2SLC6A3
SCHEMBL2213827 0.83 HIF1A (0.47) HIF1ASMN1; SMN2TDP1SLC6A2SLC6A3
SCHEMBL28057311 0.81 HIF1A (0.46) HIF1ASMN1; SMN2TDP1SLC6A2SLC6A3
SCHEMBL9902800 0.77 ALDH1A1 (0.48) HIF1ASMN1; SMN2TDP1SLC6A2SLC6A3
SCHEMBL418323 0.77 TDP1 (0.47) HIF1ASMN1; SMN2TDP1SLC6A2SLC6A3
SCHEMBL11472853 0.76 TDP1 (0.44) HIF1ASMN1; SMN2TDP1SLC6A2SLC6A3
SCHEMBL24361875 0.74 KMT2A (0.47) TDP1SLC6A2SLC6A3KMT2APTPN1
SCHEMBL8694819 0.74 SMN1; SMN2 (0.48) HIF1ASMN1; SMN2TDP1SLC6A2SLC6A3
SCHEMBL11169149 0.73 CA1 (0.40) HIF1ASMN1; SMN2TDP1SLC6A2SLC6A3
SCHEMBL13688683 0.73 ALDH1A1 (0.41) HIF1ASMN1; SMN2TDP1SLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014027849-A1 POLYMERIZABLE COMPOSITION FOR EPOXY ACRYLIC OPTICAL MATERIAL, AND METHOD FOR PREPARING EPOXY ACRYLIC OPTICAL MATERIAL 주식회사 케이오씨솔루션 (KR) 2014-02-20 WO disclosed
EP-1873168-B1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES BRIDGESTONE CORP (JP) 2012-12-12 EP disclosed
US-7968652-B2 Modified conjugated diene copolymer, rubber compositions and tires BRIDGESTONE CORPORATION (JP) 2011-06-28 US disclosed
US-20100160530-A1 RUBBER COMPOSITION CONTAINING MODIFIED POLYBUTADIENE RUBBER AND TIRE BRIDGESTRONE CORPORATION (JP) 2010-06-24 US disclosed
US-20090292043-A1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES BRIDGESTONE CORPORATION (JP) 2009-11-26 US disclosed
EP-1975200-A1 RUBBER COMPOSITION CONTAINING MODIFIED POLYBUTADIENE RUBBER AND TIRE Bridgestone Corporation (JP) 2008-10-01 EP disclosed
EP-1873168-A1 MODIFIED CONJUGATED DIENE COPOLYMER, RUBBER COMPOSITIONS AND TIRES Bridgestone Corporation (JP) 2008-01-02 EP disclosed
CN-1229449-C Malic acid diester surfactant AIR PROD & CHEM (US) 2005-11-30 CN disclosed
US-6969738-B2 Malic acid diester surfactants AIR PRODUCTS AND CHEMICALS, INC. (US) 2005-11-29 US disclosed
US-20020103280-A1 Malic acid diester surfactants LASSILA KEVIN RODNEY (US) 2002-08-01 US disclosed
US-6369146-B1 AN AQUEOUS ORGANIC COATING COMPRISING A RESIN, SURFACTANT, WETTING AGENT, FLOW AND LEVELING AGENTS AND AN HYDROXY DIALKYL(C3-6) MALEATE; REDUCED EQUILIBRIUM AND DYNAMIC SURFACE TENSION; COATINGS; INKS; ADHESIVES; HERBICIDES AIR PRODUCTS AND CHEMICALS, INC. 2002-04-09 US disclosed
CN-1302833-A Malic acid diester surfactant AIR PROD & CHEM (US) 2001-07-11 CN disclosed
EP-1095988-A2 Malic acid diester surfactants AIR PRODUCTS AND CHEMICALS, INC. (US) 2001-05-02 EP disclosed