Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | KMO | O15229 | 1/20 | 0.46 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.45 |
| ▸ | SCN4A | P35499 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22063717 | 0.81 | SMN1; SMN2 (1.00) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL17697185 | 0.81 | ASIC3 (0.65) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18731738 | 0.81 | ASIC3 (0.65) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29730373 | 0.81 | ASIC3 (0.65) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL284286 | 0.80 | ASIC3 (0.71) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL29406194 | 0.78 | ASIC3 (0.68) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL28218682 | 0.78 | ASIC3 (0.68) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL27904874 | 0.78 | ASIC3 (0.68) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2194874 | 0.76 | CYP1A2 (0.59) | NPC1RAB9ACYP1A2CYP2C9CYP2C19 | |
| SCHEMBL20220275 | 0.76 | MAPK1 (0.68) | NPC1RAB9ACYP2C19SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082627-A1 | Certain aromatic monocycles as kinase modulators | CGI PHARMACEUTICALS, INC. | 2004-04-29 | — | — | US | disclosed |
| WO-2004000820-A2 | CERTAIN AROMATIC MONOCYCLES AS KINASE MODULATORS | CELLULAR GENOMICS, INC. (US) | 2003-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082627-A1 | Certain aromatic monocycles as kinase modulators | MAP3K20, MAP3K1, MAP3K19 | NPC1 3477/4885RAB9A 2270/4885CYP1A2 2476/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.