SCHEMBL6737014

SCHEMBL6737014

NC(=O)CC1CN(S(=O)(=O)C=Cc2ccc(Cl)cc2O)CC(CC(=O)N=O)N1C(=O)c1cnc(-c2ccncc2)nc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6737011 0.85 F10 (0.31)
SCHEMBL6737017 0.85 F10 (0.31)
SCHEMBL6730855 0.81 F10 (0.41)
SCHEMBL6737022 0.80 F10 (0.32)
SCHEMBL6791200 0.79 F10 (0.43)
SCHEMBL6728962 0.79 F10 (0.49)
SCHEMBL6726198 0.76 F10 (0.34)
SCHEMBL6726195 0.76 F10 (0.34)
SCHEMBL6737025 0.76 F10 (0.33)
SCHEMBL6737020 0.76 F10 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6747023-B1 INHIBITORS FOR ACTIVATED COAGULATION FACTOR X, COAGULATION SUPPRESSORS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-06-08 US disclosed
US-20040082611-A1 Anticoagulants; brain disorders; respiratory system disorders; side effect reduction DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-04-29 US disclosed
EP-1104754-A1 NOVEL SULFONYL DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2001-06-06 EP disclosed