SCHEMBL6791200

SCHEMBL6791200

NC(=O)CC1CN(S(=O)(=O)c2cc3ccc(Cl)cc3s2)CC(CC(=O)N=O)N1C(=O)c1cnc(-c2ccncc2)nc1

nearest known ligand 0.43

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
F10 P00742 20/20 0.43
F2 P00734 1/20 0.40
KCNH2 Q12809 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6730855 0.87 F10 (0.41) F10F2
SCHEMBL6791197 0.85 F10 (0.45) F10F2KCNH2
SCHEMBL6728962 0.83 F10 (0.49) F10
SCHEMBL6737040 0.81 F10 (0.44) F10F2
SCHEMBL6921178 0.80 F10 (0.43) F10F2KCNH2
SCHEMBL6734778 0.80 F10 (0.43) F10F2KCNH2
SCHEMBL6737014 0.79
SCHEMBL6727756 0.78 F10 (0.41) F10F2
SCHEMBL6735011 0.78 F10 (0.41) F10F2
SCHEMBL6735068 0.77 F10 (0.41) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6747023-B1 INHIBITORS FOR ACTIVATED COAGULATION FACTOR X, COAGULATION SUPPRESSORS DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-06-08 US disclosed
EP-1104754-A1 NOVEL SULFONYL DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2001-06-06 EP disclosed