Dimethylcarbate

Dimethylcarbate

SCHEMBL673767

CN(C)C(=O)[O-].CN(C)C(=O)[O-].CN(C)C(=O)[O-].[Cr+3]

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.44
TSHR P16473 2/20 0.44
CA1 P00915 4/20 0.43
HSD17B10 Q99714 3/20 0.39
MAPT P10636 2/20 0.39
NFKB1 P19838 1/20 0.39
THPO P40225 1/20 0.39
APEX1 P27695 1/20 0.39
PMP22 Q01453 1/20 0.39
CA4 P22748 3/20 0.38
TAS2R38 P59533 1/20 0.38
CA12 O43570 2/20 0.35
CA2 P00918 2/20 0.35
CA9 Q16790 2/20 0.35
TP53 P04637 2/20 0.33
HPGD P15428 2/20 0.33
ALOX15 P16050 2/20 0.33
ALOX12 P18054 2/20 0.33
MAPK1 P28482 2/20 0.33
TDP1 Q9NUW8 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dimethylcarbate SCHEMBL28489364 0.92 ALDH1A1 (0.44) ALDH1A1TSHRCA1HSD17B10MAPT
Dimethylcarbate SCHEMBL1873905 0.92 ALDH1A1 (0.44) ALDH1A1TSHRCA1HSD17B10MAPT
Dimethylcarbate SCHEMBL28491926 0.92 ALDH1A1 (0.44) ALDH1A1TSHRCA1HSD17B10MAPT
Dimethylcarbate SCHEMBL672819 0.92 ALDH1A1 (0.44) ALDH1A1TSHRCA1HSD17B10MAPT
Dimethylcarbate SCHEMBL639148 0.92 ALDH1A1 (0.44) ALDH1A1TSHRCA1HSD17B10MAPT
Dimethylcarbate SCHEMBL672821 0.92 ALDH1A1 (0.44) ALDH1A1TSHRCA1HSD17B10MAPT
Dimethylcarbate SCHEMBL149385 0.92 ALDH1A1 (0.44) ALDH1A1TSHRCA1HSD17B10MAPT
Dimethylcarbate SCHEMBL6868659 0.92 ALDH1A1 (0.44) ALDH1A1TSHRCA1HSD17B10MAPT
Dimethylcarbate SCHEMBL673574 0.92 ALDH1A1 (0.44) ALDH1A1TSHRCA1HSD17B10MAPT
Dimethylcarbate SCHEMBL672828 0.92 ALDH1A1 (0.44) ALDH1A1TSHRCA1HSD17B10MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120252979-A1 Process for Producing Blends of Syndiotactic, 1,2-Polybutadiene and Rubbery Elastomers RADEMACHER CHRISTINE (US) 2012-10-04 US disclosed
US-8067503-B2 Process for producing blends of syndiotactic, 1,2-polybutadiene and rubbery elastomers BRIDGESTONE CORPORATION (JP) 2011-11-29 US disclosed
US-20070161748-A1 PROCESS FOR PRODUCING BLENDS OF SYNDIOTACTIC, 1,2-POLYBUTADIENE AND RUBBERY ELASTOMERS BRIDGESTONE CORPORATION 2007-07-12 US disclosed
US-20040242780-A1 using a catalyst that is based on a chromium-containing compound, a hydrogen phosphite, and an organomagnesium compound, or a catalyst based on a molybdenum or iron-compound, a hydrogen phosphite and organoaluminum compound; tire sidewalls; obviates the need for high-temperature mixing BRIDGESTONE CORPORATION (JP) 2004-12-02 US disclosed
WO-2003040231-A1 PROCESS FOR PRODUCING BLENDS OF SYNDIOTACTIC 1,2-POLYBUTADIENE AND RUBBERY ELASTOMERS BRIDGESTONE CORPORATION (JP) 2003-05-15 WO disclosed
US-6528588-B2 Polymerization of 1,3-butadiene in the presence of a catalyst made of a chromium compound, a hydrogen phosphite, an organomagnesium compound, a molybdenum containing compound and an organoaluminum compound BRIDGESTONE CORPORATION (JP) 2003-03-04 US disclosed
US-6465585-B2 REACTION PRODUCT OF A CHROMIUM CONTAINING COMPOUND, AN ORGANOMAGNESIUM COMPOUND AND A SILYL PHOSPHONATE BRIDGESTONE CORPORATION (JP) 2002-10-15 US disclosed
US-20020115558-A1 CHROMIUM-BASED CATALYST COMPOSITION FOR PRODUCING CONJUGATED DIENE POLYMERS BRIDGESTONE CORP. 2002-08-22 US disclosed
US-20020037967-A1 Process for producing blends of syndiotactic 1,2-polybutadiene and rubbery elastomers with a chromium-based catalyst system BRIDGESTONE CORPORATION (JP) 2002-03-28 US disclosed
US-6291591-B1 PROVIDING MIXTURE OF RUBBER CEMENT AND 1,3-BUTADIENE; POLYMERIZING 1,3-BUTADIENE BY USING A CATALYST WHICH IS COMBINATION OF OR THE REACTION PRODUCT OF CHROMIUM COMPOUND, HYDROGEN PHOSPHITE, ORGANOMAGNESIUM COMPOUND BRIDGESTONE CORPORATION (JP) 2001-09-18 US disclosed