SCHEMBL673775

SCHEMBL673775

C=C(C)C(=O)OCC(O)COCC(O)CC1CO1

nearest known ligand 0.54

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.54
TSHR P16473 3/20 0.44
THRB P10828 1/20 0.35
TP53 P04637 1/20 0.30
CYP3A4 P08684 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12076563 0.84 ALDH1A1 (0.49) ALDH1A1TSHRTHRB
SCHEMBL7867270 0.83 ALDH1A1 (0.59) ALDH1A1TSHRTHRBTP53CYP3A4
SCHEMBL5535254 0.83 TSHR (0.61) ALDH1A1TSHRTHRBCYP3A4
SCHEMBL347487 0.83 TSHR (0.61) ALDH1A1TSHRTHRBCYP3A4
SCHEMBL28511001 0.82 ALDH1A1 (0.50) ALDH1A1TSHRTHRB
SCHEMBL9797749 0.81 ALDH1A1 (0.56) ALDH1A1TSHRTHRBTP53CYP3A4
SCHEMBL673774 0.80 ALDH1A1 (0.48) ALDH1A1TSHR
SCHEMBL28954002 0.78 TSHR (0.41) ALDH1A1TSHRTP53CYP3A4
Ethylene Glycol SCHEMBL11168150 0.78 TSHR (0.55) ALDH1A1TSHRTHRBCYP3A4
SCHEMBL94906 0.78 TSHR (0.68) ALDH1A1TSHRTHRBCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6194511-B1 COMPRISING POLYMERIZABLE MONOMER CONTAINING SULFUR-CONTAINING (METH)ACRYLATE POLYMERIZABLE MONOMER AND PHOTOCHROMIC COMPOUND TOKUYAMA CORPORATION (JP) 2001-02-27 US claimed
US-6022496-A Chromene compound TOKUYAMA CORPORATION (JP) 2000-02-08 US claimed
US-5776376-A BLEND OF EPOXY AND UNSATURATED ESTER MONOMERS TOKUYAMA CORPORATION (JP) 1998-07-07 US claimed
EP-0559439-B1 Photochromic composition TOKUYAMA CORP (JP) 1997-06-04 EP claimed
US-5395566-A Addition polymerizable composition, epoxy monomer, imide or anhydride containing fused ring photochromic compound, lenses TOKUYAMA CORPORATION (JP) 1995-03-07 US claimed
EP-0619358-A1 Photochromic composition TOKUYAMA CORPORATION (JP) 1994-10-12 EP claimed
EP-0559439-A2 Photochromic composition TOKUYAMA CORPORATION (JP) 1993-09-08 EP claimed
WO-2024018902-A1 LAYERED BODY, OPTICAL ARTICLE, LENS, AND SPECTACLES 株式会社トクヤマ 2024-01-25 WO disclosed
US-11879097-B2 Photochromic compound, curable composition containing said photochromic compound, and optical article TOKUYAMA CORPORATION (JP) 2024-01-23 US disclosed
CN-111989382-B Photochromic compound, curable composition containing the same, and optical article 株式会社德山 2024-01-05 CN disclosed
CN-115151549-B Photochromic cyclic compound and curable composition containing the same 株式会社德山 2023-12-19 CN disclosed
US-20230260669-A1 CURABLE COMPOSITION AND CURED BODY OF SAME TOKUYAMA CORPORATION (JP) 2023-08-17 US disclosed
CN-116194515-A Photochromic compound, photochromic curable composition, cured product, lens and spectacles 株式会社德山 2023-05-30 CN disclosed
US-5808100-A DURABILITY TOKUYAMA CORPORATION (JP) 1998-09-15 US disclosed
US-5776376-A BLEND OF EPOXY AND UNSATURATED ESTER MONOMERS TOKUYAMA CORPORATION (JP) 1998-07-07 US disclosed
EP-0778276-A1 Photochromic chromene derivatives TOKUYAMA CORPORATION (JP) 1997-06-11 EP disclosed
US-5631382-A PHOTOCHROMIC LENSES TOKUYAMA CORPORATION (JP) 1997-05-20 US disclosed
EP-0773273-A1 PROCESS FOR THE PRODUCTION OF PHOTOCHROMIC PRODUCT OF CURING TOKUYAMA CORPORATION (JP) 1997-05-14 EP disclosed
EP-0773272-A1 PHOTOCHROMIC CURABLE COMPOSITION TOKUYAMA CORPORATION (JP) 1997-05-14 EP disclosed
EP-0696582-A1 Polycyclic spirophthalimide derivatives, process for their preparation and their use as fulgimides TOKUYAMA CORPORATION (JP) 1996-02-14 EP disclosed