Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | RBP4 | P02753 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28292173 | 0.83 | ALDH1A1 (0.46) | ALDH1A1TDP1TSHRCA2RXRA | |
| SCHEMBL10893077 | 0.82 | ALDH1A1 (0.40) | ALDH1A1TSHRCA2GAALMNA | |
| SCHEMBL1148444 | 0.82 | ALDH1A1 (0.50) | ALDH1A1TDP1TSHRCA2ATM | |
| SCHEMBL30663932 | 0.80 | ALDH1A1 (0.48) | ALDH1A1TDP1TSHRCA2ATM | |
| SCHEMBL39249 | 0.80 | ALDH1A1 (0.56) | ALDH1A1TDP1TSHRCA2RXRA | |
| SCHEMBL7537141 | 0.80 | ALDH1A1 (0.48) | ALDH1A1TDP1TSHRCA2RXRA | |
| SCHEMBL31028133 | 0.80 | ALDH1A1 (0.56) | ALDH1A1TDP1TSHRCA2RXRA | |
| SCHEMBL360806 | 0.80 | ALDH1A1 (0.48) | ALDH1A1TDP1TSHRCA2ATM | |
| SCHEMBL4787076 | 0.78 | ALDH1A1 (0.54) | ALDH1A1TDP1TSHRCA2RXRA | |
| SCHEMBL10960705 | 0.78 | ALDH1A1 (0.54) | ALDH1A1TDP1TSHRCA2RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6693158-B2 | ORGANONITROGEN, ORGANOOXYGEN POLYMER | NATIONAL SCIENCE COUNCIL (TW) | 2004-02-17 | — | — | US | disclosed |
| US-20030109656-A1 | Electroluminiscent conjugated polymers modified with high eletronegative heterocyclic moieties and their applications in polymeric light emitting diodes | NATIONAL SCIENCE COUNCIL TAIWAN CORPORATION (TW) | 2003-06-12 | — | — | US | disclosed |
| US-6495644-B1 | CONTAINING HETEROCYCLIC GROUPS SUCH AS 1,3,4-OXADIAZOLE-DIYL, 1,3,4-THIADIAZOLE-DIYL AND 1,2,4-TRIAZOLE-DIYL; HIGH EXTERNAL QUANTUM EFFICIENCY | NATIONAL SCIENCE COUNCIL (TW) | 2002-12-17 | — | — | US | disclosed |