Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | PPARD | Q03181 | 7/20 | 0.48 |
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | TSHR | P16473 | 6/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4896865 | 1.00 | LMNA (0.53) | LMNAEPHX2GPR84PPARGPPARD | |
| SCHEMBL10414871 | 1.00 | LMNA (0.53) | LMNAEPHX2GPR84PPARGPPARD | |
| SCHEMBL4896833 | 1.00 | LMNA (0.53) | LMNAEPHX2GPR84PPARGPPARD | |
| SCHEMBL8087700 | 1.00 | LMNA (0.53) | LMNAEPHX2GPR84PPARGPPARD | |
| SCHEMBL8092417 | 1.00 | LMNA (0.53) | LMNAEPHX2GPR84PPARGPPARD | |
| Ammonia Solution, Strong SCHEMBL29597283 | 0.98 | LMNA (0.52) | LMNAEPHX2GPR84PPARGPPARD | |
| SCHEMBL791222 | 0.98 | LMNA (0.50) | LMNAEPHX2GPR84PPARGPPARD | |
| SCHEMBL793167 | 0.94 | TSHR (0.52) | LMNAEPHX2GPR84PPARGPPARD | |
| SCHEMBL7768019 | 0.92 | LMNA (0.61) | LMNAEPHX2TSHRALDH1A1MEN1 | |
| SCHEMBL11041078 | 0.92 | LMNA (0.61) | LMNAEPHX2TSHRALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6686428-B2 | TRANSMETALLATION REAGENTS REACTED WITH ALPHA-HALOCARBONYL COMPOUNDS IN THE PRESENCE OF A METAL CATALYST | THE PENN STATE RESEARCH FOUNDATION | 2004-02-03 | — | — | US | disclosed |
| US-20020193543-A1 | Transmetallation reagents reacted with alpha-halocarbonyl compounds in the presence of a metal catalyst | NATIONAL INSTITUTES OF HEALTH | 2002-12-19 | — | — | US | disclosed |