Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.54 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | PARP1 | P09874 | 1/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.37 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | PARP12 | Q9H0J9 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.37 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.37 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6230351 | 0.92 | MAPK1 (0.59) | MAPK1HSD17B10CYP2C9NR1I2NPY5R | |
| SCHEMBL6239964 | 0.91 | MAPK1 (0.58) | MAPK1HSD17B10CYP2C9NR1I2NPY5R | |
| SCHEMBL6234807 | 0.90 | MAPK1 (0.61) | MAPK1HSD17B10CYP2C9NR1I2MAPT | |
| SCHEMBL6231895 | 0.88 | MAPK1 (0.58) | MAPK1HSD17B10CYP2C9NR1I2MAPT | |
| SCHEMBL6232944 | 0.87 | MAPK1 (0.59) | MAPK1HSD17B10CYP2C9NR1I2MAPT | |
| SCHEMBL6267540 | 0.85 | CYP2C9 (0.61) | MAPK1HSD17B10CYP2C9NR1I2TP53 | |
| SCHEMBL6239797 | 0.84 | CYP2C9 (0.59) | MAPK1HSD17B10CYP2C9NR1I2TP53 | |
| SCHEMBL6241366 | 0.84 | MAPK1 (0.54) | MAPK1HSD17B10CYP2C9NR1I2TP53 | |
| SCHEMBL6239211 | 0.84 | MAPK1 (0.54) | MAPK1HSD17B10CYP2C9NR1I2MAPT | |
| SCHEMBL6235652 | 0.84 | MAPK1 (0.68) | MAPK1HSD17B10CYP2C9NR1I2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1535151-A | Novel anti-infectives | ʷ��˿�������ȳ�ķ����˾ | 2004-10-06 | — | — | CN | claimed |
| US-20040147739-A1 | Novel anti-infectives | SMITHKLINE BEECHAM CORPORATION | 2004-07-29 | — | — | US | claimed |
| CN-1535151-A | Novel anti-infectives | ʷ��˿�������ȳ�ķ����˾ | 2004-10-06 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040147739-A1 | Novel anti-infectives | RPL5, RPL7, RPL35 | MAPK1 3699/4885HSD17B10 1428/4885CYP2C9 1218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.