⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6742431 | 0.93 | — | — | |
| SCHEMBL19883172 | 0.76 | — | — | |
| SCHEMBL420939 | 0.73 | — | — | |
| SCHEMBL7981 | 0.73 | — | — | |
| SCHEMBL15460010 | 0.65 | — | — | |
| SCHEMBL8560 | 0.65 | — | — | |
| SCHEMBL21841979 | 0.65 | NOS3 (0.33) | — | |
| SCHEMBL726600 | 0.65 | — | — | |
| SCHEMBL8461479 | 0.62 | TRIM24 (0.38) | — | |
| SCHEMBL20509292 | 0.62 | TRIM24 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024137329-A1 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS AND INTERMEDIATES THEREOF | ALEXION PHARMACEUTICALS, INC. (US) | 2024-06-27 | — | — | WO | disclosed |
| EP-4008321-A1 | FLUOROCYCLOPENTENYLCYTOSINE FOR TREATING TUMOUR | Ocuphire Pharma, Inc. (US) | 2022-06-08 | — | — | EP | disclosed |
| EP-3307251-B1 | FLUOROCYCLOPENTENYLCYTOSINE USES AND PROCESSES OF PREPARATION | REXAHN PHARMACEUTICALS INC (US) | 2021-10-20 | — | — | EP | disclosed |
| US-6686509-B2 | Process for producing α, α-difluorocycloalkane compound | MITSUI CHEMICALS, INC. (JP) | 2004-02-03 | — | — | US | disclosed |
| US-20030078460-A1 | Process for producing alpha, alpha-difluorocycloalkane compound | MITSUI CHEMICALS, INC. (JP) | 2003-04-24 | — | — | US | disclosed |