SCHEMBL6738822

SCHEMBL6738822

CCOP(=S)(OCC)SCn1nc(C(C)C)sc1=O.CCOP(=S)(OCC)SCn1nc(OC(C)C)sc1=O

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 2/20 0.32
LMNA P02545 1/20 0.32
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
ALDH1A1 P00352 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL118303 0.93 MEN1 (0.35) HSD17B10LMNACYP3A4HPGDTDP1
Methidathion SCHEMBL1068991 0.85 ALDH1A1 (0.35) HSD17B10LMNACYP3A4HPGDTDP1
SCHEMBL6479136 0.82 ALDH1A1 (0.47) ALDH1A1MEN1KMT2ATSHR
SCHEMBL121376 0.80 MEN1 (0.37) HSD17B10LMNACYP3A4HPGDTDP1
Methidathion SCHEMBL1276216 0.75 KDM4E (0.31) HSD17B10LMNACYP3A4HPGDALDH1A1
Methidathion SCHEMBL5264915 0.74 ALDH1A1 (0.37) HSD17B10LMNACYP3A4HPGDTDP1
SCHEMBL1069689 0.74 ALDH1A1 (0.37) HSD17B10LMNACYP3A4HPGDTDP1
Pirimiphos Methyl SCHEMBL5917231 0.73 TDP1 (0.52) HSD17B10CYP3A4TDP1ALDH1A1TSHR
SCHEMBL7876087 0.71 ALDH1A1 (0.42) HSD17B10LMNACYP3A4HPGDALDH1A1
SCHEMBL116389 0.71 ALDH1A1 (0.42) HSD17B10LMNACYP3A4HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6680065-B2 FOR TREATMENT OF WOODY PLANTS; EMPLOYED IN HOLLOW PREFORMED IN THE WOODY PLANT BAYER AKTIENGESELLSCHAFT (DE) 2004-01-20 US disclosed
US-6528079-B2 For treatment of woody plants; employed in a hollow preformed in the woody plant BAYER AKTIENGESELLSCHAFT (DE) 2003-03-04 US disclosed
US-20020061323-A1 SHAPED BODIES WHICH RELEASE AGROCHEMICAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2002-05-23 US disclosed
US-20010039248-A1 Shaped bodies which release agrochemical active substances PODSZUN WOLFGANG (DE) 2001-11-08 US disclosed
EP-0564945-B1 A method of controlling harmful insects BAYER AGROCHEM KK (JP) 2001-01-24 EP disclosed
US-6063393-A RODS OR PINS TO BE PRESSED INTO PLANTS NIHON BAYER AGROCHEM K.K. (JP) 2000-05-16 US disclosed
EP-0564945-A1 A method of controlling harmful insects NIHON BAYER AGROCHEM K.K. (JP) 1993-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020061323-A1 SHAPED BODIES WHICH RELEASE AGROCHEMICAL ACTIVE SUBSTANCES AGL, CHMP4B, GUSB HSD17B10 548/4885LMNA 1302/4885CYP3A4 645/4885
US-20010039248-A1 Shaped bodies which release agrochemical active substances AGL, CHMP4B, GUSB HSD17B10 572/4885LMNA 1288/4885CYP3A4 686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.