SCHEMBL6739100

SCHEMBL6739100

Cc1c(C(F)(F)F)cnc(-c2cc3c(cc2F)NC(=O)CO3)c1Cl

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NR3C2 P08235 11/20 0.40
PGR P06401 5/20 0.40
MCL1 Q07820 1/20 0.38
POLB P06746 2/20 0.38
MMP12 P39900 1/20 0.38
PDE3B Q13370 1/20 0.36
PDE3A Q14432 1/20 0.36
NR3C1 P04150 1/20 0.35
PKM P14618 1/20 0.35
MAPK1 P28482 1/20 0.35
MAPT P10636 3/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8565740 0.77 NR3C2 (0.46) NR3C2PGRMCL1POLBNR3C1
SCHEMBL6726966 0.76 NR3C2 (0.38) NR3C2PGRMCL1POLBMMP12
SCHEMBL6743760 0.74 PTAFR (0.32)
SCHEMBL8487377 0.73 NR3C2 (0.46) NR3C2PGRMCL1POLBMMP12
SCHEMBL7556544 0.73 NR3C2 (0.46) NR3C2PGRMCL1POLBPDE3B
SCHEMBL8177519 0.72 NR3C2 (0.41) NR3C2PGRPOLBMMP12PDE3B
SCHEMBL8699332 0.71 MAPT (0.41) NR3C2PGRMCL1POLBPKM
SCHEMBL24855112 0.70 MMP12 (0.46) NR3C2PGRMMP12PKMMAPK1
SCHEMBL6743960 0.69 KDM4E (0.33) POLB
SCHEMBL6742514 0.69 COMT (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040043903-A1 Herbicides; applying to plants BASF AKTIENGESELLSCHAFT (DE) 2004-03-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040043903-A1 Herbicides; applying to plants DDT, DRD1, DRD4 NR3C2 1370/4885PGR 4565/4885MCL1 1920/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.