Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8220855 | 0.98 | HRH3 (0.50) | CARM1PRMT6PRMT8SCN5AHRH3 | |
| SCHEMBL13822725 | 0.91 | ACE2 (0.48) | SCN5ASMN1; SMN2ALDH1A1PAOXACE2 | |
| SCHEMBL5910693 | 0.89 | HRH3 (0.57) | CARM1PRMT6PRMT8SCN5AHRH3 | |
| SCHEMBL21348139 | 0.88 | ALDH1A1 (0.52) | CARM1PRMT6PRMT8SCN5AHRH3 | |
| SCHEMBL7446808 | 0.86 | CARM1 (0.56) | CARM1PRMT6PRMT8HRH3ALDH1A1 | |
| SCHEMBL17526224 | 0.86 | HRH3 (0.55) | CARM1PRMT6PRMT8SCN5AHRH3 | |
| SCHEMBL5911217 | 0.86 | HRH3 (0.62) | CARM1PRMT6PRMT8SCN5AHRH3 | |
| SCHEMBL17526233 | 0.86 | HRH3 (0.55) | CARM1PRMT6PRMT8SCN5AHRH3 | |
| SCHEMBL21348177 | 0.86 | HRH3 (0.52) | CARM1PRMT6PRMT8SCN5AHRH3 | |
| SCHEMBL13655836 | 0.85 | ACE2 (0.43) | SMN1; SMN2ALDH1A1KDM4EPAOXACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230149910-A1 | CATALYST COMPOSITION | MOMENTIVE PERFORMANCE MATERIALS INC. | 2023-05-18 | — | — | US | disclosed |
| US-9717694-B2 | Peptide/particle delivery systems | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-08-01 | — | — | US | disclosed |
| US-9717694-B2 | Peptide/particle delivery systems | THE JOHNS HOPKINS UNIVERSITY (US) | 2017-08-01 | — | — | US | disclosed |
| US-20160374949-A9 | PEPTIDE/PARTICLE DELIVERY SYSTEMS | THE JOHNS HOPKINS UNIVERSITY (US) | 2016-12-29 | — | — | US | disclosed |
| US-8992991-B2 | Multicomponent degradable cationic polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-03-31 | — | — | US | disclosed |
| US-8992991-B2 | Multicomponent degradable cationic polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2015-03-31 | — | — | US | disclosed |
| US-20120128782-A1 | Multicomponent Degradable Cationic Polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-05-24 | — | — | US | disclosed |
| US-20120128782-A1 | Multicomponent Degradable Cationic Polymers | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-05-24 | — | — | US | disclosed |
| US-20120114759-A1 | PEPTIDE/PARTICLE DELIVERY SYSTEMS | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-05-10 | — | — | US | disclosed |
| US-20120114759-A1 | PEPTIDE/PARTICLE DELIVERY SYSTEMS | THE JOHNS HOPKINS UNIVERSITY (US) | 2012-05-10 | — | — | US | disclosed |
| US-RE38415-E1 | POLYMERIZATION CATALYSTS SUCH AS N-(3-AMINOPROPYL)PYRROLIDINE USED FOR COPOLYMERIZATION OR CONDENSATION POLYMERIZATION OF POLYURETHANES, POLYUREAURETHANE COPOLYMERS OR POLYUREAS | BAYER AKTIENGESELLSCHAFT (DE) | 2004-02-03 | — | — | US | disclosed |
| EP-0495249-B1 | Use of N-(aminoalkyl)-pyrrolidines as a catalyst for the polyisocyanate-poly-addition process, process for the preparation of polyurethane-ureas | BAYER AG (DE) | 1994-07-27 | — | — | EP | disclosed |
| US-5134217-A | Forming polyurethanes modified with chain extension agents for foams | BAYER AKTIENGESELLSCHAFT (DE) | 1992-07-28 | — | — | US | disclosed |
| EP-0495249-A1 | Use of N-(aminoalkyl)-pyrrolidines as a catalyst for the polyisocyanate-poly-addition process, process for the preparation of polyurethane-ureas | BAYER AG (DE) | 1992-07-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160374949-A9 | PEPTIDE/PARTICLE DELIVERY SYSTEMS | VEGFA, IAPP, FLT1 | CARM1 4787/4885PRMT6 3542/4885PRMT8 4203/4885 |
| US-20120114759-A1 | PEPTIDE/PARTICLE DELIVERY SYSTEMS | VEGFA, IAPP, FLT1 | CARM1 4787/4885PRMT6 3542/4885PRMT8 4203/4885 |
| US-20120128782-A1 | Multicomponent Degradable Cationic Polymers | PEF1, FIBP, PARN | CARM1 2255/4885PRMT6 1969/4885PRMT8 1899/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.