SCHEMBL673933

SCHEMBL673933

c1ccc(C2=C3CCC3c3ccccc32)cc1

nearest known ligand 0.60

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP11B2 P19099 3/20 0.35
USP30 Q70CQ3 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNA4 P43681 1/20 0.33
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
BRD4 O60885 1/20 0.31
HRH1 P35367 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5820471 0.77 TAAR1 (0.48) CHRNB2CHRNA4GAAMAPTTDP1
SCHEMBL3255766 0.73 DDB1 (0.38) HRH1
SCHEMBL3248563 0.72 DDB1 (0.37) HRH1
SCHEMBL29187306 0.70 ADRA1A (0.45) CYP11B2
SCHEMBL6561469 0.69 DDB1 (0.34)
SCHEMBL30788464 0.68 ADRA1A (0.43) CYP11B2
SCHEMBL9789468 0.67 CYP1A2 (0.36)
SCHEMBL16393627 0.63 BRD4 (0.51) CYP11B2CHRNB2CHRNA4BRD4
SCHEMBL19380843 0.63 DDB1 (0.47) LMNAMAPT
SCHEMBL2484478 0.63 DDB1 (0.47) LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2085135-A1 GLOBULAR RUBBER ADJUVANTS AND THE METHOD OF PREPARATING THE SAME Jiangsu Sinorgchem Technology Co., Ltd (CN) 2009-08-05 EP claimed
EP-2085135-B1 METHOD OF PREPARATING GLOBULAR RUBBER ADJUVANTS JIANGSU SINORGCHEM TECH CO LTD (CN) 2013-02-13 EP disclosed
US-8349230-B2 Spherical rubber chemicals and the method for preparing the same JIANGSU SINORGCHEM TECHNOLOGY CO., LTD. (CN) 2013-01-08 US disclosed
US-20120139140-A1 Spherical Rubber Chemicals and the Method for Preparing the Same Jiangsu Sinorgchem Technolgy Co., LTD (CN) 2012-06-07 US disclosed
US-8066919-B2 Spherical rubber chemicals and the method for preparing the same JIANGSU SINORGCHEM TECHNOLOGY CO., LTD. (CN) 2011-11-29 US disclosed
US-20100314789-A1 GLOBULAR RUBBER ADJUVANTS AND THE METHOD OF PREPARATING THE SAME SENNICS CO., LTD. (CN) 2010-12-16 US disclosed
EP-2085135-A1 GLOBULAR RUBBER ADJUVANTS AND THE METHOD OF PREPARATING THE SAME Jiangsu Sinorgchem Technology Co., Ltd (CN) 2009-08-05 EP disclosed