SCHEMBL6739583

SCHEMBL6739583

CCCCCCCCCCCCCCCCCCCCOC(=O)Cl

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 1/20 0.61
EPHX1 P07099 1/20 0.57
TSHR P16473 4/20 0.55
HCAR2 Q8TDS4 1/20 0.52
RAD52 P43351 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
ACHE P22303 6/20 0.50
ALDH1A1 P00352 3/20 0.50
FAAH O00519 1/20 0.50
DGKA P23743 1/20 0.50
LMNA P02545 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10621483 1.00 NAAA (0.61) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL335168 1.00 NAAA (0.61) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL1206999 1.00 NAAA (0.61) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL323128 1.00 NAAA (0.61) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL7129437 1.00 NAAA (0.61) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL5836729 1.00 NAAA (0.61) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL11131653 1.00 NAAA (0.61) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL6740298 1.00 NAAA (0.61) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL11132543 1.00 NAAA (0.61) NAAAEPHX1TSHRHCAR2RAD52
SCHEMBL184446 1.00 NAAA (0.61) NAAAEPHX1TSHRHCAR2RAD52

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113332305-B Lipid composition of cytidine compound 中国医学科学院医药生物技术研究所 2022-08-16 CN disclosed
CN-113336816-B Cytidine compounds and anti-tumor application thereof 中国医学科学院医药生物技术研究所 2022-05-17 CN disclosed
CN-112724088-B Uracil compound and anti-tumor application thereof 中国医学科学院医药生物技术研究所 2022-04-29 CN disclosed
CN-112724088-A Uracil compound and anti-tumor application thereof 中国医学科学院医药生物技术研究所 2021-04-30 CN disclosed
CN-112618550-A Antineoplastic uracil compound and lipid composition thereof 中国医学科学院医药生物技术研究所 2021-04-09 CN disclosed
US-6686462-B2 Antiviral compounds and methods of administration THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-02-03 US disclosed
WO-1998038202-A1 ANTIVIRAL PHOSPHONATE PRODRUGS OF NUCLEOSIDES AND NUCLEOSIDE ANALOGUES DANA-FARBER CANCER INSTITUTE (US) 1998-09-03 WO disclosed
EP-0044085-B1 NOVEL NUCLEOSIDE DERIVATIVES Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1983-05-25 EP disclosed
US-4367332-A N4 -Alkoxycarbonylarabinofuranosylcytosine ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1983-01-04 US disclosed
EP-0044085-A1 Novel nucleoside derivatives Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1982-01-20 EP disclosed