Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | MIF | P14174 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.50 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29612324 | 1.00 | HTT (0.52) | HTTNPSR1NPC1HPGDMAPK1 | |
| Methane SCHEMBL27924017 | 0.98 | HTT (0.50) | HTTNPSR1NPC1HPGDMAPK1 | |
| SCHEMBL27685437 | 0.95 | KAT8 (0.54) | HTTALOX15ALDH1A1LMNAHSD17B10 | |
| SCHEMBL107937 | 0.93 | KAT8 (0.56) | HTTALOX15ALDH1A1LMNAHSD17B10 | |
| SCHEMBL28387660 | 0.93 | KAT8 (0.56) | HTTALOX15ALDH1A1LMNAHSD17B10 | |
| SCHEMBL994580 | 0.93 | KAT8 (0.56) | HTTALOX15ALDH1A1LMNAHSD17B10 | |
| SCHEMBL8975192 | 0.93 | KAT8 (0.56) | HTTALOX15ALDH1A1LMNAHSD17B10 | |
| SCHEMBL106675 | 0.93 | KAT8 (0.56) | HTTALOX15ALDH1A1LMNAHSD17B10 | |
| SCHEMBL109409 | 0.93 | KAT8 (0.56) | HTTALOX15ALDH1A1LMNAHSD17B10 | |
| Water SCHEMBL27338163 | 0.92 | KAT8 (0.55) | HTTALOX15ALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109661415-A | The method for reducing the aldehyde discharge of polyurethane foam | 科思创德国股份有限公司 | 2019-04-19 | — | — | CN | claimed |
| US-9162969-B2 | Nitrooxyesters, their preparation and use | DSM IP ASSETS B.V. (NL) | 2015-10-20 | — | — | US | claimed |
| US-8709110-B2 | Use of carotenoid (ester)s | DSM IP ASSETS B.V. (NL) | 2014-04-29 | — | — | US | claimed |
| US-20120210634-A1 | NITROOXYESTERS, THEIR PREPARATION AND USE | DSM IP ASSETS B.V. (NL) | 2012-08-23 | — | — | US | claimed |
| CN-102382135-A | Preparation method of organic phosphate polypropylene nucleating agent | CHINA PETROLEUM & CHEMICAL | 2012-03-21 | — | — | CN | claimed |
| CN-101367833-B | Preparation method for organic phosphate nucleating agent | CHINA PETROCHEMICAL CO LTD | 2011-06-15 | — | — | CN | claimed |
| US-20110119995-A1 | NOVEL USE OF CAROTENOID (ESTER)S | DSM IP ASSETS B.V. (NL) | 2011-05-26 | — | — | US | claimed |
| CN-102040628-A | Method for preparing polypropylene nucleating agent | CHINA PETROLEUM & CHEMICAL | 2011-05-04 | — | — | CN | claimed |
| CN-102040629-A | Method for preparing organic phosphate nucleating agent | CHINA PETROLEUM & CHEMICAL | 2011-05-04 | — | — | CN | claimed |
| CN-101423624-B | Miniaturization organic phoshate nucleating agent and preparation method thereof | CHINA PETROLEUM & CHEMICAL | 2011-05-04 | — | — | CN | claimed |
| WO-2007089645-A2 | BIODIESEL FUEL ADDITIVE | ORYXE ENERGY INTERNATIONAL, INC. (US) | 2007-08-09 | — | — | WO | claimed |
| US-20060201056-A1 | Biodiesel fuel additive | ORYXE ENERGY INTERNATIONAL, INC. (US) | 2006-09-14 | — | — | US | claimed |
| CN-1185240-C | Process for one-stage synthesizing substituted diaryl organic metal phosphate | SHANGHAI SHENGLIN NEW MATERIAL (CN) | 2005-01-19 | — | — | CN | claimed |
| CN-1358728-A | Process for one-stage synthesizing substituted diaryl organic metal phosphate | SHANGHAI CHENGLIN NEW MATERIAL (CN) | 2002-07-17 | — | — | CN | claimed |
| CN-1032362-C | Method of stabilizing oxymethylene copolymer | UBE INDUSTRIES (JP) | 1996-07-24 | — | — | CN | claimed |
| EP-0427456-B1 | STABILIZER COMPOSITIONS | ETHYL CORPORATION (US) | 1993-09-01 | — | — | EP | claimed |
| US-5076814-A | Stabilizer compositions | ETHYL CORPORATION (US) | 1991-12-31 | — | — | US | claimed |
| US-5024775-A | Alkyl phenol stabilizer compositions for fuels and lubricants | ETHYL CORPORATION (US) | 1991-06-18 | — | — | US | claimed |
| EP-0427456-A1 | Stabilizer compositions | ETHYL CORPORATION (US) | 1991-05-15 | — | — | EP | claimed |
| CN-1039814-A | The method of stabilized oxymethylene copolymer | UBE INDUSTRIES (JP) | 1990-02-21 | — | — | CN | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120210634-A1 | NITROOXYESTERS, THEIR PREPARATION AND USE | CYP2E1, CYP1B1, CYP11B1 | HTT 4115/4885NPSR1 1703/4885NPC1 1178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.