SCHEMBL8975192

SCHEMBL8975192

CCCCCCc1ccc(O)c(C(C)(C)C)c1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KAT8 Q9H7Z6 2/20 0.56
PTGS2 P35354 3/20 0.53
ESR1 P03372 2/20 0.53
ADRA2A P08913 2/20 0.53
ADORA3 P0DMS8 2/20 0.53
TACR2 P21452 2/20 0.53
SLC6A2 P23975 2/20 0.53
SLC6A4 P31645 2/20 0.53
SLC6A3 Q01959 2/20 0.53
ALDH1A1 P00352 2/20 0.53
LMNA P02545 2/20 0.53
HSD17B10 Q99714 2/20 0.53
KDM4E B2RXH2 1/20 0.53
SHBG P04278 1/20 0.53
TP53 P04637 1/20 0.53
CYP3A4 P08684 1/20 0.53
HSPD1 P10809 1/20 0.53
ADRB3 P13945 1/20 0.53
HTR2C P28335 1/20 0.53
HSPE1 P61604 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL106675 1.00 KAT8 (0.56) KAT8PTGS2ESR1ADRA2AADORA3
SCHEMBL28387660 1.00 KAT8 (0.56) KAT8PTGS2ESR1ADRA2AADORA3
SCHEMBL994580 1.00 KAT8 (0.56) KAT8PTGS2ESR1ADRA2AADORA3
SCHEMBL109409 1.00 KAT8 (0.56) KAT8PTGS2ESR1ADRA2AADORA3
SCHEMBL107937 1.00 KAT8 (0.56) KAT8PTGS2ESR1ADRA2AADORA3
Water SCHEMBL27338163 0.98 KAT8 (0.55) KAT8PTGS2ESR1ADRA2AADORA3
SCHEMBL27685437 0.98 KAT8 (0.54) KAT8PTGS2ESR1ADRA2AADORA3
SCHEMBL29106645 0.94 KAT8 (0.51) KAT8PTGS2ESR1ADRA2AADORA3
SCHEMBL29612324 0.93 HTT (0.52) KAT8PTGS2ESR1ADRA2AADORA3
SCHEMBL673963 0.93 HTT (0.52) KAT8PTGS2ESR1ADRA2AADORA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102807474-A Preparation methods of substituted diaryl phenol, organophosphorus ester and organic phosphate CHINA PETROLEUM & CHEMICAL 2012-12-05 CN disclosed
CN-102807582-A Preparation methods of organic phosphate ester and organic phosphate nucleating agent CHINA PETROLEUM & CHEMICAL 2012-12-05 CN disclosed
EP-0593653-B1 POLYMERIZATION PROCESS AND PRODUCTS SHELL OIL CO (US) 1996-09-25 EP disclosed
EP-0588800-B1 POLYMERIZATION PROCESS AND PRODUCTS SHELL OIL CO (US) 1996-04-17 EP disclosed
EP-0595979-B1 POLYMERIZATION PROCESS FOR CYCLOOLEFINS SHELL OIL CO (US) 1996-03-20 EP disclosed
EP-0595979-A1 POLYMERIZATION PROCESS AND PRODUCTS. SHELL OIL CO (US) 1994-05-11 EP disclosed
EP-0593653-A1 POLYMERIZATION PROCESS AND PRODUCTS. SHELL OIL CO (US) 1994-04-27 EP disclosed
EP-0588800-A1 POLYMERIZATION PROCESS AND PRODUCTS. SHELL OIL CO (US) 1994-03-30 EP disclosed
WO-1993002121-A1 POLYMERIZATION PROCESS AND PRODUCTS SHELL OIL COMPANY (US) 1993-02-04 WO disclosed
WO-1993001223-A1 POLYMERIZATION PROCESS AND PRODUCTS SHELL OIL COMPANY (US) 1993-01-21 WO disclosed
WO-1992022597-A1 POLYMERIZATION PROCESS AND PRODUCTS SHELL OIL COMPANY (US) 1992-12-23 WO disclosed
US-5143992-A Methathesis polymerizable adducts of a divinylcyclohydrocarbon and cyclopentadiene SHELL OIL COMPANY (US) 1992-09-01 US disclosed
US-5095082-A Polymerization process employing mixture of Diels-Alder adducts of 4-vinylcyclohexene and cyclopentadiene SHELL OIL COMPANY (US) 1992-03-10 US disclosed