⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8460149 | 0.94 | — | — | |
| SCHEMBL300448 | 0.94 | — | — | |
| SCHEMBL7914 | 0.88 | — | — | |
| SCHEMBL7359 | 0.84 | — | — | |
| SCHEMBL6524 | 0.80 | — | — | |
| SCHEMBL54025 | 0.80 | — | — | |
| SCHEMBL721796 | 0.80 | — | — | |
| SCHEMBL10340141 | 0.80 | ALDH1A1 (0.36) | — | |
| SCHEMBL14562886 | 0.73 | — | — | |
| SCHEMBL11028224 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1681 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118344363-A | Tricyclic fused ring derivatives and uses thereof | 广东东阳光药业股份有限公司 | 2024-07-16 | — | — | CN | claimed |
| CN-117279932-B | Esatitecan derivatives and linker-carriers and conjugates thereof | 启德医药科技（苏州）有限公司 | 2024-07-05 | — | — | CN | claimed |
| CN-113214222-B | N- (arylsulfonyl) -indole-2-carboxamide FBPase inhibitors and uses thereof | 中国医学科学院药物研究所 | 2024-06-21 | — | — | CN | claimed |
| WO-2024125651-A1 | NOVEL ACRYLIC ACID DERIVATIVE WITH HETEROCYCLE SUBSTITUTION AND USE THEREOF | 津药生物科技（天津）有限公司 | 2024-06-20 | — | — | WO | claimed |
| US-11999748-B2 | Exatecan derivatives, linker-payloads, and conjugates and thereof | GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD. (CN) | 2024-06-04 | — | — | US | claimed |
| WO-2024104344-A1 | QUINOLINECARBOXYLIC ACID DERIVATIVE AND USE THEREOF | 沈阳中化农药化工研发有限公司 | 2024-05-23 | — | — | WO | claimed |
| WO-2024104345-A1 | PYRIDAZINONE DERIVATIVE AND USE THEREOF | 沈阳中化农药化工研发有限公司 | 2024-05-23 | — | — | WO | claimed |
| CN-118047724-A | Pyridazinone derivative and application thereof | 沈阳中化农药化工研发有限公司 | 2024-05-17 | — | — | CN | claimed |
| CN-118047721-A | Quinoline carboxylic acid derivative and application thereof | 沈阳中化农药化工研发有限公司 | 2024-05-17 | — | — | CN | claimed |
| EP-4349813-A1 | QUATERNARY AMMONIUM SALT COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | Yichang Humanwell Pharmaceutical Co., Ltd. (CN) | 2024-04-10 | — | — | EP | claimed |
| WO-1998057921-A1 | METHOD FOR PREPARING 4-(ALKYL)-3-ALKOXY-ANILINE COMPOUNDS | MERIAL (FR) | 1998-12-23 | — | — | WO | claimed |
| US-5705646-A | Substituted pyrazoles as CRF antagonists | PFIZER INC. (US) | 1998-01-06 | — | — | US | claimed |
| EP-0674625-B1 | AMINO-SUBSTITUTED PYRAZOLES HAVING CRF ANTAGONISTIC ACTIVITY | PFIZER (US) | 1997-12-10 | — | — | EP | claimed |
| US-5668145-A | Amino-substituted pyrazoles having CRF antagonistic activity | PFIZER INC. (US) | 1997-09-16 | — | — | US | claimed |
| EP-0764153-A1 | SUBSTITUTED PYRAZOLES HAVING CORTICOTROPIN-RELEASING FACTOR (CRF) ANTAGONIST ACTIVITY | PFIZER INC. (US) | 1997-03-26 | — | — | EP | claimed |
| WO-1995033727-A1 | SUBSTITUTED PYRAZOLES HAVING CORTICOTROPIN-RELEASING FACTOR (CRF) ANTAGONIST ACTIVITY | PFIZER INC. (US) | 1995-12-14 | — | — | WO | claimed |
| EP-0674625-A1 | AMINO-SUBSTITUTED PYRAZOLES HAVING CRF ANTAGONISTIC ACTIVITY | PFIZER INC. (US) | 1995-10-04 | — | — | EP | claimed |
| EP-0674631-A1 | SUBSTITUTED PYRAZOLES AS CRF ANTAGONISTS | PFIZER INC. (US) | 1995-10-04 | — | — | EP | claimed |
| WO-1994013644-A1 | AMINO-SUBSTITUTED PYRAZOLES HAVING CRF ANTAGONISTIC ACTIVITY | PFIZER INC. (US) | 1994-06-23 | — | — | WO | claimed |
| WO-1994013661-A1 | SUBSTITUTED PYRAZOLES AS CRF ANTAGONISTS | PFIZER INC. (US) | 1994-06-23 | — | — | WO | claimed |