Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 4/20 | 0.36 |
| ▸ | ICAM1 | P05362 | 4/20 | 0.36 |
| ▸ | ITGAL | P20701 | 4/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | RHEB | Q15382 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.34 |
| ▸ | F10 | P00742 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5830005 | 0.85 | ITGAL (0.42) | ITGB2ICAM1ITGALALDH1A1SMN1; SMN2 | |
| SCHEMBL6740151 | 0.85 | HTT (0.35) | ITGB2ICAM1ITGALALDH1A1SMN1; SMN2 | |
| SCHEMBL6740154 | 0.83 | ITGAL (0.36) | ITGB2ICAM1ITGALALDH1A1SMN1; SMN2 | |
| SCHEMBL5830013 | 0.78 | ITGAL (0.39) | ITGB2ICAM1ITGALHRH3ALDH1A1 | |
| SCHEMBL5830504 | 0.78 | MAPT (0.50) | ITGB2ICAM1ITGALALDH1A1SMN1; SMN2 | |
| SCHEMBL5830727 | 0.76 | ITGAL (0.57) | ITGB2ICAM1ITGALALDH1A1SMN1; SMN2 | |
| SCHEMBL5830859 | 0.76 | ITGAL (0.57) | ITGB2ICAM1ITGALALDH1A1SMN1; SMN2 | |
| SCHEMBL5830843 | 0.73 | ALDH1A1 (0.46) | ITGB2ICAM1ITGALALDH1A1SMN1; SMN2 | |
| SCHEMBL5830012 | 0.72 | TP53 (0.41) | ITGB2ICAM1ITGALALDH1A1MEN1 | |
| SCHEMBL7849244 | 0.71 | ITGAL (0.50) | ITGB2ICAM1ITGALALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116518-A1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES | 2004-06-17 | — | — | US | claimed |