Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 20/20 | 0.62 |
| ▸ | ITGB2 | P05107 | 18/20 | 0.62 |
| ▸ | ICAM1 | P05362 | 18/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5830014 | 0.86 | ITGAL (0.66) | ITGALITGB2ICAM1 | |
| SCHEMBL27524481 | 0.82 | ITGAL (0.59) | ITGALITGB2ICAM1 | |
| SCHEMBL6740154 | 0.79 | ITGAL (0.36) | ITGALITGB2ICAM1 | |
| SCHEMBL7839031 | 0.79 | ITGAL (0.68) | ITGALITGB2ICAM1 | |
| SCHEMBL5830508 | 0.79 | ITGAL (0.71) | ITGALITGB2ICAM1 | |
| SCHEMBL7613089 | 0.79 | ITGAL (0.71) | ITGALITGB2ICAM1 | |
| SCHEMBL5830848 | 0.78 | ITGAL (0.77) | ITGALITGB2ICAM1 | |
| SCHEMBL5830736 | 0.77 | ITGAL (1.00) | ITGALITGB2ICAM1 | |
| SCHEMBL5830866 | 0.77 | ITGAL (1.00) | ITGALITGB2ICAM1 | |
| SCHEMBL27492009 | 0.74 | ITGAL (0.73) | ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040116518-A1 | Cell adhesion-inhibiting antiinflammatory and immune-suppressive compounds | ABBOTT LABORATORIES | 2004-06-17 | — | — | US | claimed |