Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 19/20 | 0.68 |
| ▸ | ITGB2 | P05107 | 18/20 | 0.68 |
| ▸ | ICAM1 | P05362 | 18/20 | 0.68 |
| ▸ | GPR183 | P32249 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5830848 | 0.90 | ITGAL (0.77) | ITGALITGB2ICAM1GPR183 | |
| SCHEMBL27551793 | 0.86 | ITGAL (0.69) | ITGALITGB2ICAM1GPR183 | |
| SCHEMBL5830009 | 0.82 | ITGAL (0.46) | ITGALITGB2ICAM1GPR183 | |
| SCHEMBL5830736 | 0.82 | ITGAL (1.00) | ITGALITGB2ICAM1 | |
| SCHEMBL5830014 | 0.81 | ITGAL (0.66) | ITGALITGB2ICAM1 | |
| SCHEMBL5830866 | 0.80 | ITGAL (1.00) | ITGALITGB2ICAM1 | |
| SCHEMBL6740156 | 0.79 | ITGAL (0.62) | ITGALITGB2ICAM1 | |
| SCHEMBL5830012 | 0.78 | TP53 (0.41) | ITGALITGB2ICAM1 | |
| SCHEMBL27473980 | 0.77 | ITGAL (0.91) | ITGALITGB2ICAM1 | |
| SCHEMBL27524481 | 0.77 | ITGAL (0.59) | ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140814-A2 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039081-A2 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-07-06 | — | — | WO | disclosed |