Fenobucarb

Fenobucarb

SCHEMBL6740176

CCC(C)c1ccccc1OC(=O)NC.CCC(C)c1ccccc1OC(=O)NC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.58
ACHE P22303 1/20 0.58
PGR P06401 1/20 0.50
GAA P10253 1/20 0.50
PTGS1 P23219 1/20 0.50
MAPK1 P28482 1/20 0.50
HSD17B10 Q99714 1/20 0.50
TSHR P16473 1/20 0.47
KDM4E B2RXH2 3/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
KMT2A Q03164 2/20 0.47
CYP1A2 P05177 1/20 0.45
CES2 O00748 1/20 0.43
NISCH Q9Y2I1 1/20 0.43
CHRM2 P08172 1/20 0.41
CHRM4 P08173 1/20 0.41
CHRM5 P08912 1/20 0.41
CHRM1 P11229 1/20 0.41
CHRM3 P20309 1/20 0.41
LMNA P02545 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fenobucarb SCHEMBL73674 1.00 ALDH1A1 (0.58) ALDH1A1ACHEPGRGAAPTGS1
Fenobucarb SCHEMBL29368514 1.00 ALDH1A1 (0.58) ALDH1A1ACHEPGRGAAPTGS1
SCHEMBL11465498 0.86 KDM4E (0.51) ALDH1A1ACHEGAATSHRKDM4E
SCHEMBL23610497 0.86 ALDH1A1 (0.55) ALDH1A1ACHEPGRGAAPTGS1
Fenobucarb SCHEMBL7946601 0.85 ALDH1A1 (0.44) ALDH1A1ACHEPGRGAAPTGS1
SCHEMBL27374412 0.84 ALDH1A1 (0.54) ALDH1A1ACHEPGRGAAPTGS1
Isoprocarb SCHEMBL64155 0.83 ALDH1A1 (0.65) ALDH1A1ACHEPGRGAAPTGS1
Isoprocarb SCHEMBL6739739 0.83 ALDH1A1 (0.65) ALDH1A1ACHEPGRGAAPTGS1
Isoprocarb SCHEMBL29365297 0.83 ALDH1A1 (0.65) ALDH1A1ACHEPGRGAAPTGS1
SCHEMBL1790848 0.83 TSHR (0.53) ALDH1A1PTGS1HSD17B10TSHRKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6680065-B2 FOR TREATMENT OF WOODY PLANTS; EMPLOYED IN HOLLOW PREFORMED IN THE WOODY PLANT BAYER AKTIENGESELLSCHAFT (DE) 2004-01-20 US disclosed
US-6528079-B2 For treatment of woody plants; employed in a hollow preformed in the woody plant BAYER AKTIENGESELLSCHAFT (DE) 2003-03-04 US disclosed
US-20020061323-A1 SHAPED BODIES WHICH RELEASE AGROCHEMICAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2002-05-23 US disclosed
US-20010039248-A1 Shaped bodies which release agrochemical active substances PODSZUN WOLFGANG (DE) 2001-11-08 US disclosed
EP-0564945-B1 A method of controlling harmful insects BAYER AGROCHEM KK (JP) 2001-01-24 EP disclosed
US-6063393-A RODS OR PINS TO BE PRESSED INTO PLANTS NIHON BAYER AGROCHEM K.K. (JP) 2000-05-16 US disclosed
EP-0564945-A1 A method of controlling harmful insects NIHON BAYER AGROCHEM K.K. (JP) 1993-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020061323-A1 SHAPED BODIES WHICH RELEASE AGROCHEMICAL ACTIVE SUBSTANCES AGL, CHMP4B, GUSB ALDH1A1 729/4885ACHE 250/4885PGR 3736/4885
US-20010039248-A1 Shaped bodies which release agrochemical active substances AGL, CHMP4B, GUSB ALDH1A1 758/4885ACHE 251/4885PGR 3742/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.