Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 1/20 | 0.49 |
| ▸ | PDE5A | O76074 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 5/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 5/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6743401 | 0.80 | ABCG2 (0.61) | PDE5AALDH1A1HSD17B10MAPK1HTT | |
| SCHEMBL6739817 | 0.77 | HDAC3 (0.49) | PDE5AHPGDHSD17B10MAPTLMNA | |
| SCHEMBL31194517 | 0.74 | PDE5A (0.43) | VNN1PDE5AALDH1A1KDM4EHPGD | |
| SCHEMBL31663591 | 0.72 | ABCG2 (0.62) | HSD17B10TSHRABCB1ABCG2ABCC1 | |
| SCHEMBL2479265 | 0.72 | MMP3 (0.52) | ALDH1A1GAATSHRABCB1ABCG2 | |
| SCHEMBL31612415 | 0.71 | ABCG2 (0.54) | KDM4EHPGDGAALMNATSHR | |
| SCHEMBL22073476 | 0.71 | ABCG2 (0.54) | KDM4EHPGDGAALMNATSHR | |
| SCHEMBL21849416 | 0.71 | ABCG2 (0.54) | ALDH1A1HPGDTSHRABCB1ABCG2 | |
| SCHEMBL29450769 | 0.71 | ABCG2 (0.54) | ALDH1A1HPGDTSHRABCB1ABCG2 | |
| SCHEMBL6737053 | 0.71 | HPGD (0.48) | ALDH1A1HPGDMAPK1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082627-A1 | Certain aromatic monocycles as kinase modulators | CGI PHARMACEUTICALS, INC. | 2004-04-29 | — | — | US | disclosed |
| WO-2004000820-A2 | CERTAIN AROMATIC MONOCYCLES AS KINASE MODULATORS | CELLULAR GENOMICS, INC. (US) | 2003-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082627-A1 | Certain aromatic monocycles as kinase modulators | MAP3K20, MAP3K1, MAP3K19 | VNN1 4584/4885PDE5A 2755/4885ALDH1A1 2999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.