SCHEMBL674051

SCHEMBL674051

C=CC(=O)OCC[Si](C)(C)OC

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.50
ALDH1A1 P00352 4/20 0.50
TP53 P04637 3/20 0.50
HIF1A Q16665 3/20 0.50
CYP3A4 P08684 2/20 0.50
HPGD P15428 1/20 0.50
HSD17B10 Q99714 1/20 0.50
THRB P10828 2/20 0.42
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL81411 0.89 TSHR (0.57) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL16536849 0.87 TSHR (0.60) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL29947896 0.86 TSHR (0.63) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL29965060 0.86 TSHR (0.63) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL29965640 0.86 TSHR (0.63) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL29965109 0.86 TSHR (0.63) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL16537330 0.86 TSHR (0.63) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL16286692 0.86 TSHR (0.63) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL9302488 0.85 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL733859 0.85 TSHR (0.50) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119161381-A Hydrophobic monomer and preparation method thereof, polymer and preparation method and application thereof 中国石油化工股份有限公司 2024-12-20 CN claimed
US-8053528-B2 Binder compositions for fiber mats, and fiber mats and articles comprising them GEORGIA-PACIFIC CHEMICALS LLC (US) 2011-11-08 US claimed
EP-2164902-A1 BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM Georgia-Pacific Chemicals LLC (US) 2010-03-24 EP claimed
US-20090124151-A1 BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM GEORGIA-PACIFIC CHEMICALS LLC (US) 2009-05-14 US claimed
WO-2008150647-A1 BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM GEORGIA-PACIFIC CHEMICALS, LLC (US) 2008-12-11 WO claimed
CN-119161381-A Hydrophobic monomer and preparation method thereof, polymer and preparation method and application thereof 中国石油化工股份有限公司 2024-12-20 CN disclosed
CN-118290609-A Modified oligomeric chitosan and preparation method thereof, copolymer and preparation method and application thereof, and drilling fluid 中国石油化工股份有限公司 2024-07-05 CN disclosed
US-20240018358-A1 POLYSILOXANE-BASED RESIN AND UTILIZATION THEREOF KANEKA CORPORATION (JP) 2024-01-18 US disclosed
CN-117265895-A Solvent-free environment-friendly low-viscosity high-performance printing silica gel and preparation method thereof 广东聚思新材料科技有限公司 2023-12-22 CN disclosed
CN-117136204-A Polysiloxane resin and use thereof 株式会社钟化 2023-11-28 CN disclosed
WO-2023119928-A1 METHOD FOR PRODUCING DISPERSION LIQUID OR SOLUTION IN WHICH WATER CONTAINING POLYSILOXANE-BASED RESIN SERVES AS MEDIUM 株式会社カネカ 2023-06-29 WO disclosed
CN-111533854-B Silicon modified acrylic resin and application thereof 上海亿祺化工技术有限公司 2023-03-31 CN disclosed
US-9266981-B2 Conjugated diene random copolymer having alkoxysilane unit KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2016-02-23 US disclosed
US-20150065639-A1 CONJUGATED DIENE RANDOM COPOLYMER HAVING ALKOXYSILANE UNIT KOREA KUMHO PETROCHEMICAL CO., LTD. (KR) 2015-03-05 US disclosed
US-8053528-B2 Binder compositions for fiber mats, and fiber mats and articles comprising them GEORGIA-PACIFIC CHEMICALS LLC (US) 2011-11-08 US disclosed
EP-2164902-A1 BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM Georgia-Pacific Chemicals LLC (US) 2010-03-24 EP disclosed
US-20090124151-A1 BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM GEORGIA-PACIFIC CHEMICALS LLC (US) 2009-05-14 US disclosed
WO-2008150647-A1 BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM GEORGIA-PACIFIC CHEMICALS, LLC (US) 2008-12-11 WO disclosed
EP-1711537-A1 CURABLE COMPOSITION CONTAINING SURFACE-MODIFIED PARTICLES Consortium für elektrochemische Industrie GmbH (DE) 2006-10-18 EP disclosed
WO-2005092932-A1 CURABLE COMPOSITION CONTAINING SURFACE-MODIFIED PARTICLES Consortium für elektrochemische Industrie GmbH (DE) 2005-10-06 WO disclosed