SCHEMBL733859

SCHEMBL733859

C=CC(=O)OCC[Si](C)(OC)OC

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.50
ALDH1A1 P00352 4/20 0.50
TP53 P04637 3/20 0.50
HIF1A Q16665 3/20 0.50
CYP3A4 P08684 2/20 0.50
HPGD P15428 1/20 0.50
HSD17B10 Q99714 1/20 0.50
THRB P10828 2/20 0.42
MAPK1 P28482 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ATM Q13315 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL80818 0.89 TSHR (0.57) TSHRALDH1A1TP53HIF1ACYP3A4
Ethylene SCHEMBL28626350 0.87 TSHR (0.55) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL6151224 0.87 TSHR (0.60) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL29737749 0.86 TSHR (0.63) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL29964436 0.86 TSHR (0.63) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL25277799 0.86 TSHR (0.63) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL29737742 0.86 TSHR (0.63) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL16537403 0.86 TSHR (0.63) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL21402789 0.86 TSHR (0.63) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL16286522 0.86 TSHR (0.63) TSHRALDH1A1TP53HIF1ACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 341 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220220352-A1 Curable Silicone Optically Clear Adhesives and Uses Thereof HENKEL AG & CO KGAA (DE) 2022-07-14 US claimed
CN-110997853-A Curable silicone optically clear adhesives and uses thereof 汉高知识产权控股有限责任公司 2020-04-10 CN claimed
EP-3268411-A1 A POLYORGANOSILOXANE AND A MOISTURE AND RADIATION CURABLE ADHESIVE COMPOSITION COMPRISING THE SAME Henkel IP & Holding GmbH (DE) 2018-01-17 EP claimed
WO-2016141547-A1 A POLYORGANOSILOXANE AND A MOISTURE AND RADIATION CURABLE ADHESIVE COMPOSITION COMPRISING THE SAME Henkel IP Holding GmbH (DE) 2016-09-15 WO claimed
CN-101679722-B Binder compositions for fiber mats, and fiber mats and articles comprising them GEORGIA PACIFIC CHEMICALS LLC 2012-08-29 CN claimed
CN-101679722-A Binder compositions for fiber mats, and fiber mats and articles comprising them GEORGIA PACIFIC CHEMICALS LLC 2010-03-24 CN claimed
US-20090124151-A1 BINDER COMPOSITIONS FOR FIBER MATS, AND FIBER MATS AND ARTICLES COMPRISING THEM GEORGIA-PACIFIC CHEMICALS LLC (US) 2009-05-14 US claimed
US-12637598-B2 Heat-crosslinkable adhesive composition forming a heat-stable adhesive seal BOSTIK SA (FR) 2026-05-26 US disclosed
EP-4284844-B1 AQUEOUS POLYMER LATEX BASF SE (DE) 2026-05-20 EP disclosed
EP-4727905-A1 COMPOSITIONS FOR CONSTRUCTION PURPOSES BASF SE (DE) 2026-04-22 EP disclosed
EP-3898748-B1 NOVEL HEAT-CURABLE COMPOSITIONS AND SELF-ADHESIVE ARTICLES THEREOF BOSTIK SA (FR) 2026-04-01 EP disclosed
US-12584022-B2 Solvochromic effect pigments, method of production and use thereof ECKART GMBH (DE) 2026-03-24 US disclosed
EP-3887452-B2 RADAR FREQUENCY TRANSPARENT EFFECT PIGMENT MIXTURE, FORMULATIONS AND COATINGS THEREOF ECKART GMBH (DE) 2026-01-14 EP disclosed
US-5695851-A CROSSLINKABLE, POLYMERIZABLE COMPOSITION CONTAINING (METH)ACRYLOYLOXY GROUPS, SILICA WHOSE SURFACE HAS BEEN MODIFIED WITH AN ORGANOSILANE-CONTAINING COMPOUND, AND A HIGH ENERGY RADIATION POLYMERIZATION INITIATOR MITSUBISHI RAYON CO., LTD. (JP) 1997-12-09 US disclosed
EP-0534753-B1 Composite composition having high transparency and process for producing same MITSUBISHI RAYON CO (JP) 1996-12-18 EP disclosed
EP-0708143-A1 Polyvinyl chloride based resin composition and products derived therefrom SEKISUI AMERICA CORPORATION (US) 1996-04-24 EP disclosed
EP-0696621-A1 COATING COMPOSITION AND SURFACE-COATED MOLDING PRODUCED THEREWITH MITSUBISHI RAYON CO., LTD. (JP) 1996-02-14 EP disclosed
US-5385988-A A curable blends consisting of an additional polymer and a polysilicates, polysiloxanes or polysilsesquioxanes in a dispersion system of colloidal silica to form rigid, tough interpenetrating polymer networks MITSUBISHI RAYON CO., LTD. (JP) 1995-01-31 US disclosed
EP-0534753-A1 Composite composition having high transparency and process for producing same MITSUBISHI RAYON CO., LTD. (JP) 1993-03-31 EP disclosed
US-4026826-A ALKOXYSILANES JAPAN ATOMIC ENERGY RESEARCH INSTITUTE (JA) 1977-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12584022-B2 Solvochromic effect pigments, method of production and use thereof PPOX, TDO2, SCO2 TSHR 1099/4885ALDH1A1 2915/4885TP53 114/4885
US-12637598-B2 Heat-crosslinkable adhesive composition forming a heat-stable adhesive seal HSPA1A, HSPB1, HSPA1B TSHR 4860/4885ALDH1A1 87/4885TP53 3908/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.