Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7168985 | 0.92 | PTGER4 (0.41) | PTGER4VCAM1ALDH3A1ALDH1A3ALDH1A1 | |
| SCHEMBL6334825 | 0.90 | PTGER4 (0.38) | PTGER4VCAM1ALDH3A1ALDH1A3ALDH1A1 | |
| SCHEMBL6741615 | 0.79 | HSD17B10 (0.39) | VCAM1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL6743936 | 0.76 | KDM4E (0.39) | ALDH1A1MAPTKDM4EMEN1RAB9A | |
| SCHEMBL6743884 | 0.74 | CHKA (0.39) | — | |
| SCHEMBL6744503 | 0.71 | HSD17B10 (0.39) | VCAM1ALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL6334754 | 0.70 | HSD17B10 (0.44) | VCAM1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL6333065 | 0.69 | HSD17B10 (0.40) | VCAM1ALDH1A1MAPTKDM4EMEN1 | |
| SCHEMBL6340569 | 0.69 | KDM4E (0.39) | VCAM1MAPTKDM4EHSD17B10 | |
| SCHEMBL1426139 | 0.66 | KDM4E (0.40) | ALDH1A1MAPTKDM4EMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1404289-A1 | 1-BENZOPYRANE-DERIVATIVES AND COLOURING AGENTS CONTAINING THE SALTS THEREOF | Wella Aktiengesellschaft (DE) | 2004-04-07 | — | — | EP | claimed |
| WO-2003000214-A1 | 1-BENZOPYRANE-DERIVATIVES AND COLOURING AGENTS CONTAINING THE SALTS THEREOF | WELLA AKTIENGESELLSCHAFT (DE) | 2003-01-03 | — | — | WO | claimed |
| EP-1404289-A1 | 1-BENZOPYRANE-DERIVATIVES AND COLOURING AGENTS CONTAINING THE SALTS THEREOF | Wella Aktiengesellschaft (DE) | 2004-04-07 | — | — | EP | disclosed |
| WO-2003000214-A1 | 1-BENZOPYRANE-DERIVATIVES AND COLOURING AGENTS CONTAINING THE SALTS THEREOF | WELLA AKTIENGESELLSCHAFT (DE) | 2003-01-03 | — | — | WO | disclosed |