Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.41 |
| ▸ | ALDH1A3 | P47895 | 5/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6334825 | 0.94 | PTGER4 (0.38) | PTGER4ALDH1A1ALDH1A3ALDH3A1MAPT | |
| SCHEMBL6740684 | 0.92 | PTGER4 (0.36) | PTGER4ALDH1A1ALDH1A3ALDH3A1MAPT | |
| SCHEMBL6334754 | 0.74 | HSD17B10 (0.44) | ALDH1A1MAPTKDM4EMEN1RAB9A | |
| SCHEMBL1426139 | 0.72 | KDM4E (0.40) | ALDH1A1MAPTKDM4EMEN1RAB9A | |
| SCHEMBL4625936 | 0.72 | KDM4E (0.44) | ALDH1A1MAPTKDM4EMEN1RAB9A | |
| Iodide SCHEMBL21436350 | 0.71 | ACHE (0.40) | ALDH1A1MAPTKDM4EMEN1RAB9A | |
| SCHEMBL6340569 | 0.70 | KDM4E (0.39) | MAPTKDM4EVCAM1HSD17B10 | |
| SCHEMBL6741615 | 0.69 | HSD17B10 (0.39) | ALDH1A1MAPTKDM4EMEN1RAB9A | |
| SCHEMBL1426018 | 0.69 | ACHE (0.38) | ALDH1A1KDM4EMEN1RAB9AKMT2A | |
| SCHEMBL4625719 | 0.67 | KDM4E (0.41) | ALDH1A1MAPTKDM4EMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030196281-A1 | 1-benzopyrane-derivatives and colouring agents containing the salts thereof | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-23 | — | — | US | claimed |
| US-20030196281-A1 | 1-benzopyrane-derivatives and colouring agents containing the salts thereof | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030196281-A1 | 1-benzopyrane-derivatives and colouring agents containing the salts thereof | KRT18, COL2A1, PHB1 | PTGER4 2667/4885ALDH1A1 9/4885ALDH1A3 200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.