SCHEMBL6740798

SCHEMBL6740798

O=C(O)c1ccc(N2C(=O)CSC2=S)cc1

nearest known ligand 0.71

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 11/20 0.71
GAA P10253 9/20 0.64
MEN1 O00255 9/20 0.64
POLB P06746 3/20 0.64
MAPT P10636 6/20 0.60
ALDH1A1 P00352 4/20 0.60
RECQL P46063 3/20 0.60
L3MBTL1 Q9Y468 3/20 0.60
MAPK1 P28482 2/20 0.60
KDM4E B2RXH2 1/20 0.60
THRB P10828 1/20 0.58
HTT P42858 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
CA12 O43570 1/20 0.57
CA1 P00915 1/20 0.57
CA9 Q16790 1/20 0.57
DDAH1 O94760 1/20 0.50
HSD17B10 Q99714 1/20 0.50
DUSP22 Q9NRW4 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11025571 0.83 CA12 (0.61) KMT2AGAAMEN1POLBMAPT
SCHEMBL3041005 0.83 KMT2A (1.00) KMT2AGAAMEN1POLBMAPT
SCHEMBL9328791 0.81 KMT2A (0.70) KMT2AGAAMEN1POLBMAPT
SCHEMBL181796 0.81 KMT2A (0.69) KMT2AGAAMEN1POLBMAPT
SCHEMBL10721761 0.80 KMT2A (0.59) KMT2AGAAMEN1POLBMAPT
SCHEMBL12726838 0.80 KMT2A (0.72) KMT2AGAAMEN1POLBMAPT
SCHEMBL11689294 0.78 KMT2A (0.70) KMT2AGAAMEN1POLBMAPT
SCHEMBL1421430 0.78 KMT2A (1.00) KMT2AGAAMEN1POLBMAPT
SCHEMBL11120643 0.77 KMT2A (0.59) KMT2AGAAMEN1POLBMAPT
SCHEMBL5471999 0.77 KMT2A (0.70) KMT2AGAAMEN1POLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9831042-B2 Organic dyes comprising a hydrazone moiety and their use in dye-sensitized solar cells BASF SE (DE) 2017-11-28 US disclosed
US-9801960-B2 Probe for a biological specimen and labelling method and screening method using the probe CANON KABUSHIKI KAISHA (JP) 2017-10-31 US disclosed
US-9801960-B2 Probe for a biological specimen and labelling method and screening method using the probe CANON KABUSHIKI KAISHA (JP) 2017-10-31 US disclosed
US-20160126022-A1 ORGANIC DYES COMPRISING A HYDRAZONE MOIETY AND THEIR USE IN DYE-SENSITIZED SOLAR CELLS BASF SE (DE) 2016-05-05 US disclosed
US-20150157745-A1 PROBE FOR A BIOLOGICAL SPECIMEN AND LABELLING METHOD AND SCREENING METHOD USING THE PROBE CANON KK (JP) 2015-06-11 US disclosed
US-20150157745-A1 PROBE FOR A BIOLOGICAL SPECIMEN AND LABELLING METHOD AND SCREENING METHOD USING THE PROBE CANON KK (JP) 2015-06-11 US disclosed
EP-2870204-A2 ORGANIC DYES COMPRISING A HYDRAZONE MOIETY AND THEIR USE IN DYE-SENSITIZED SOLAR CELLS BASF SE (DE) 2015-05-13 EP disclosed
WO-2014006544-A2 ORGANIC DYES COMPRISING A HYDRAZONE MOIETY AND THEIR USE IN DYE-SENSITIZED SOLAR CELLS BASF SE (DE) 2014-01-09 WO disclosed
US-20110243850-A1 PROBE FOR A BIOLOGICAL SPECIMEN AND LABELLING METHOD AND SCREENING METHOD USING THE PROBE CANON KABUSHIKI KAISHA (JP) 2011-10-06 US disclosed
US-20110243850-A1 PROBE FOR A BIOLOGICAL SPECIMEN AND LABELLING METHOD AND SCREENING METHOD USING THE PROBE CANON KABUSHIKI KAISHA (JP) 2011-10-06 US disclosed
EP-0047470-B1 METHOD FOR IMMUNOCHEMICAL MEASUREMENT FUJI PHOTO FILM CO., LTD. (JP) 1985-04-24 EP disclosed
US-4473652-A LABELLING WITH CYANINE OR MEROCYANINE DYE FUJI PHOTO FILM CO., LTD. (JP) 1984-09-25 US disclosed
US-4414325-A PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 1983-11-08 US disclosed
US-4375508-A ACETHYLENIC HYDROCARBON CHAIN EASTMAN KODAK COMPANY (US) 1983-03-01 US disclosed
EP-0048834-A1 Method for measurement of trace enzymes FUJI PHOTO FILM CO., LTD. (JP) 1982-04-07 EP disclosed
EP-0047470-A1 Method for immunochemical measurement FUJI PHOTO FILM CO., LTD. (JP) 1982-03-17 EP disclosed
US-4283488-A SILVER HALIDE EMULSIONS EASTMAN KODAK COMPANY (US) 1981-08-11 US disclosed
US-4108667-A Photographic compositions and elements containing benzo[a]quinolizinium methine dyes EASTMAN KODAK COMPANY (US) 1978-08-22 US disclosed
US-4003750-A METHINE DYES EASTMAN KODAK COMPANY (US) 1977-01-18 US disclosed
US-3961952-A ELECTROPHOTOGRAPHY, SUPPORTS, COATINGS ITEK CORPORATION (US) 1976-06-08 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150157745-A1 PROBE FOR A BIOLOGICAL SPECIMEN AND LABELLING METHOD AND SCREENING METHOD USING THE PROBE FUCA1, FABP2, ALPI KMT2A 4373/4885GAA 220/4885MEN1 1003/4885
US-20110243850-A1 PROBE FOR A BIOLOGICAL SPECIMEN AND LABELLING METHOD AND SCREENING METHOD USING THE PROBE FUCA1, FABP2, ALPI KMT2A 4373/4885GAA 220/4885MEN1 1003/4885
US-20160126022-A1 ORGANIC DYES COMPRISING A HYDRAZONE MOIETY AND THEIR USE IN DYE-SENSITIZED SOLAR CELLS C1S, C9, C1R KMT2A 2380/4885GAA 4509/4885MEN1 448/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.