SCHEMBL11025571

SCHEMBL11025571

O=C(O)c1ccc(N2C(=O)CSC2=O)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 7/20 0.61
CA9 Q16790 7/20 0.61
CA1 P00915 5/20 0.61
DDAH1 O94760 1/20 0.53
ALDH1A1 P00352 4/20 0.50
KMT2A Q03164 3/20 0.50
HSD17B10 Q99714 1/20 0.50
CA2 P00918 2/20 0.49
SCN2A Q99250 1/20 0.49
L3MBTL1 Q9Y468 3/20 0.47
MEN1 O00255 2/20 0.47
POLB P06746 2/20 0.47
GAA P10253 2/20 0.47
MAPT P10636 1/20 0.47
THRB P10828 1/20 0.47
HTT P42858 1/20 0.47
RECQL P46063 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
LMNA P02545 1/20 0.44
RXFP1 Q9HBX9 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6740798 0.83 KMT2A (0.71) CA12CA9CA1DDAH1ALDH1A1
SCHEMBL181733 0.80 KMT2A (0.64) ALDH1A1KMT2AL3MBTL1MEN1POLB
SCHEMBL3798127 0.77 KMT2A (0.52) ALDH1A1KMT2AL3MBTL1MEN1POLB
SCHEMBL12632654 0.77 F2 (0.52) ALDH1A1KMT2AL3MBTL1MEN1POLB
SCHEMBL6293045 0.77 MGLL (0.48) ALDH1A1KMT2AL3MBTL1MEN1POLB
SCHEMBL458085 0.76 CA12 (1.00) CA12CA9CA1DDAH1ALDH1A1
SCHEMBL11028524 0.75 CA2 (0.43) CA12CA9CA1ALDH1A1KMT2A
SCHEMBL7297607 0.72 DHODH (0.51) ALDH1A1KMT2AL3MBTL1MEN1POLB
SCHEMBL1199839 0.72 ALDH1A1 (0.74) ALDH1A1KMT2AHSD17B10L3MBTL1MEN1
SCHEMBL11020613 0.71 CA12 (0.65) CA12CA9CA1DDAH1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0048834-B1 METHOD FOR MEASUREMENT OF TRACE ENZYMES FUJI PHOTO FILM CO., LTD. (JP) 1985-06-19 EP disclosed
US-4473652-A LABELLING WITH CYANINE OR MEROCYANINE DYE FUJI PHOTO FILM CO., LTD. (JP) 1984-09-25 US disclosed
US-4414325-A PHOTOGRAPHY FUJI PHOTO FILM CO., LTD. (JP) 1983-11-08 US disclosed
EP-0048834-A1 Method for measurement of trace enzymes FUJI PHOTO FILM CO., LTD. (JP) 1982-04-07 EP disclosed
EP-0047470-A1 Method for immunochemical measurement FUJI PHOTO FILM CO., LTD. (JP) 1982-03-17 EP disclosed