Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.86 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.86 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | RAB9A | P51151 | 2/20 | 0.62 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.58 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2208450 | 0.88 | AKR1C3 (0.68) | MAPTL3MBTL1KMT2AMEN1RAB9A | |
| SCHEMBL4349056 | 0.86 | AKR1C3 (0.66) | MAPTL3MBTL1KMT2AMEN1RAB9A | |
| Nitrogen SCHEMBL7794313 | 0.83 | AKR1C3 (0.62) | MAPTL3MBTL1KMT2AMEN1RAB9A | |
| SCHEMBL18415522 | 0.83 | AKR1C3 (0.62) | MAPTL3MBTL1KMT2AMEN1RAB9A | |
| SCHEMBL23657747 | 0.82 | MAPT (0.72) | MAPTL3MBTL1KMT2AMEN1RAB9A | |
| SCHEMBL6736048 | 0.81 | PIK3CA (0.66) | MAPTL3MBTL1KMT2AMEN1MAPK1 | |
| SCHEMBL28599511 | 0.80 | HTR3E (0.73) | MAPTL3MBTL1KMT2AMEN1RAB9A | |
| SCHEMBL29656856 | 0.80 | HTR3E (0.73) | MAPTL3MBTL1KMT2AMEN1RAB9A | |
| SCHEMBL10680649 | 0.80 | AKR1C3 (0.58) | MAPTL3MBTL1KMT2AMEN1RAB9A | |
| SCHEMBL11396473 | 0.79 | MAPT (0.65) | MAPTL3MBTL1KMT2AMEN1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040082627-A1 | Certain aromatic monocycles as kinase modulators | CGI PHARMACEUTICALS, INC. | 2004-04-29 | — | — | US | claimed |
| WO-2004000820-A2 | CERTAIN AROMATIC MONOCYCLES AS KINASE MODULATORS | CELLULAR GENOMICS, INC. (US) | 2003-12-31 | — | — | WO | claimed |
| US-20040082627-A1 | Certain aromatic monocycles as kinase modulators | CGI PHARMACEUTICALS, INC. | 2004-04-29 | — | — | US | disclosed |
| WO-2004000820-A2 | CERTAIN AROMATIC MONOCYCLES AS KINASE MODULATORS | CELLULAR GENOMICS, INC. (US) | 2003-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082627-A1 | Certain aromatic monocycles as kinase modulators | MAP3K20, MAP3K1, MAP3K19 | MAPT 2507/4885L3MBTL1 2483/4885KMT2A 489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.