Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.50 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28203478 | 0.95 | USP2 (0.56) | USP2FFAR4GPR84FFAR1CAMK2A | |
| SCHEMBL7157613 | 0.93 | USP2 (0.59) | USP2FFAR4GPR84FFAR1ALDH1A1 | |
| SCHEMBL6653958 | 0.93 | USP2 (0.59) | USP2FFAR4GPR84FFAR1ALDH1A1 | |
| SCHEMBL18363555 | 0.91 | FFAR1 (0.57) | USP2FFAR4GPR84FFAR1CAMK2A | |
| SCHEMBL946974 | 0.89 | USP2 (0.53) | USP2FFAR4GPR84FFAR1CAMK2A | |
| Adipic Acid SCHEMBL7743772 | 0.87 | USP2 (0.47) | USP2FFAR4GPR84FFAR1CAMK2A | |
| Adipic Acid SCHEMBL347426 | 0.86 | USP2 (0.43) | USP2FFAR4GPR84FFAR1CAMK2A | |
| Palmitic Acid SCHEMBL28358922 | 0.86 | USP2 (0.71) | USP2FFAR4GPR84FFAR1ALDH1A1 | |
| Decanoic Acid SCHEMBL28285361 | 0.86 | USP2 (0.71) | USP2FFAR4GPR84FFAR1ALDH1A1 | |
| Dodecanoate SCHEMBL394038 | 0.85 | USP2 (0.75) | USP2FFAR4GPR84FFAR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040091982-A1 | Isocyanate free polyurethane production process via carbamate polyesterification | BAXENDEN CHEMICALS LIMITED (GB) | 2004-05-13 | — | — | US | disclosed |
| EP-1368409-A1 | ISOCYANATE FREE POLYURETHANE PRODUCTION PROCESS VIA CARBAMATE POLYESTERIFICATION | BAXENDEN CHEMICALS LIMITED (GB) | 2003-12-10 | — | — | EP | disclosed |
| WO-2002057338-A1 | ISOCYANATE FREE POLYURETHANE PRODUCTION PROCESS VIA CARBAMATE POLYESTERIFICATION | BAXENDEN CHEMICALS LIMITED (GB) | 2002-07-25 | — | — | WO | disclosed |