Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | DGKA | P23743 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL7743772 | 0.95 | USP2 (0.47) | USP2FFAR1FFAR4GPR84LMNA | |
| Adipic Acid SCHEMBL8486335 | 0.89 | FFAR1 (0.46) | FFAR1FFAR4GPR84LMNAMEN1 | |
| SCHEMBL28203478 | 0.87 | USP2 (0.56) | USP2FFAR1FFAR4GPR84LMNA | |
| SCHEMBL7134435 | 0.87 | FFAR4 (0.49) | FFAR1FFAR4GPR84LMNACAMK2A | |
| SCHEMBL17782931 | 0.87 | FFAR4 (0.49) | FFAR1FFAR4GPR84LMNACAMK2A | |
| SCHEMBL7142279 | 0.87 | FFAR4 (0.49) | FFAR1FFAR4GPR84LMNACAMK2A | |
| SCHEMBL9649626 | 0.87 | FFAR4 (0.49) | FFAR1FFAR4GPR84LMNACAMK2A | |
| Adipic Acid SCHEMBL6740995 | 0.86 | USP2 (0.51) | USP2FFAR1FFAR4GPR84LMNA | |
| SCHEMBL6653958 | 0.86 | USP2 (0.59) | USP2FFAR1FFAR4GPR84LMNA | |
| SCHEMBL7157613 | 0.86 | USP2 (0.59) | USP2FFAR1FFAR4GPR84LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 339 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113440422-A | Matte eyeliner and preparation method thereof | 上海联锴新材料有限公司 | 2021-09-28 | — | — | CN | claimed |
| US-10172783-B2 | High UV protection alcohol-free anhydrous clear system | L'OREAL (FR) | 2019-01-08 | — | — | US | claimed |
| CN-103655313-B | A kind of whitening skin and preserving moisture skin care suncream | NOX-BELLCOW (ZHONGSHAN) NONWOVEN CHEMICAL LIMITED (CN) | 2015-09-16 | — | — | CN | claimed |
| EP-1815844-B1 | Photoprotecting compositions with reduced risk of skin sensitisation | DERMATOLOGIQUES D URIAGE LAB (FR) | 2015-04-29 | — | — | EP | claimed |
| CN-104546561-A | Three-dimensional molding wax oil powder and preparation method thereof | LIXIN BIOTECH COSMETIC SHANGHAI CO LTD | 2015-04-29 | — | — | CN | claimed |
| US-20140205546-A1 | NANOSCALE PARTICLE FORMULATIONS AND METHODS | Annuary Healthcare, Inc. | 2014-07-24 | — | — | US | claimed |
| CN-103876948-A | Rana japonica oil collagen peptide moisturizing sun cream and preparation process thereof | UNIV JILIN | 2014-06-25 | — | — | CN | claimed |
| US-20140170089-A1 | PHOTOPROTECTIVE EYE CREAM AND METHODS | Taylor James, LLC (US) | 2014-06-19 | — | — | US | claimed |
| CN-103655313-A | Whitening, moisturizing, sun screening and skin caring cream | NOX BELLCOW ZHONGSHAN NONWOVEN CHEMICAL LTD | 2014-03-26 | — | — | CN | claimed |
| US-20130177504-A1 | Nanoscale Particle Formulations and Methods | Annuary Healthcare, Inc. (US) | 2013-07-11 | — | — | US | claimed |
| US-20020110571-A1 | Fiber-containing cosmetic composition | KANJI MOHAMED (US) | 2002-08-15 | — | — | US | claimed |
| WO-2002060403-A2 | HIGH OIL CLEAR EMULSION WITH ELASTOMER | COLGATE-PALMOLIVE COMPANY (US) | 2002-08-08 | — | — | WO | claimed |
| US-6426062-B1 | MIXTURE OF STARCH GRAFT POLYMER, SILICONE AND GELATION AGENT | COLGATE-PALMOLIVE COMPANY | 2002-07-30 | — | — | US | claimed |
| WO-2002049586-A2 | FIBER-CONTAINING COSMETIC COMPOSITION | L'OREAL SA (FR) | 2002-06-27 | — | — | WO | claimed |
| US-6403069-B1 | SILICONE, ANTIPERSPIRANT, SOLVENT AND EMULSIFIER | COLGATE-PALMOLIVE COMPANY | 2002-06-11 | — | — | US | claimed |
| WO-2002043490-A1 | FOAMING INSECT REPELLENT COMPOSITIONS | AVON PRODUCTS, INC. (US) | 2002-06-06 | — | — | WO | claimed |
| EP-1208836-A2 | Fiber-containing base composition for use with mascara | L'OREAL S.A. (FR) | 2002-05-29 | — | — | EP | claimed |
| US-6387357-B1 | CYCLOMETHICONE OR DIMETHICONE CROSSPOLYMER OF A POLYSILOXANE AND AN ALPHA, OMEGA DIENE; A SILICONE COPOLYOL; A VOLATILE SILICONE; ANTIPERSPIRANT AND/OR DEODORANT WATER IN OIL EMULSION | COLGATE-PALMOLIVE COMPANY | 2002-05-14 | — | — | US | claimed |
| WO-2002034212-A2 | HIGH OIL CLEAR EMULSION WITH DIENE ELASTOMER | COLGATE-PALMOLIVE COMPANY (US) | 2002-05-02 | — | — | WO | claimed |
| EP-0118876-B1 | Shaped bodies of cellular polyurethane, method for their manufacture by thermoplastic deformation of polyester-polyurethane foam and their use | BASF AG (DE) | 1993-11-10 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140205546-A1 | NANOSCALE PARTICLE FORMULATIONS AND METHODS | CUTA, S100P, KRT18 | USP2 1150/4885FFAR1 315/4885FFAR4 1041/4885 |
| US-20130177504-A1 | Nanoscale Particle Formulations and Methods | CUTA, S100P, KRT18 | USP2 1150/4885FFAR1 315/4885FFAR4 1041/4885 |
| US-20140170089-A1 | PHOTOPROTECTIVE EYE CREAM AND METHODS | CUTA, MICA, CSTB | USP2 1532/4885FFAR1 3363/4885FFAR4 3205/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.