Biphenyl

Biphenyl

SCHEMBL6741241

Cc1ccc(S(=O)(=O)N(C(N)=O)S(=O)(=O)N(C(N)=O)S(=O)(=O)c2ccc(C)cc2)cc1.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.47

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.47
CA9 Q16790 1/20 0.47
PTGES O14684 2/20 0.47
ALOX5 P09917 1/20 0.47
C5AR1 P21730 1/20 0.45
KEAP1 Q14145 2/20 0.45
NFE2L2 Q16236 2/20 0.45
TAS2R14 Q9NYV8 1/20 0.44
ADAMTS4 O75173 1/20 0.43
ALDH1A1 P00352 6/20 0.43
LMNA P02545 2/20 0.42
HTT P42858 2/20 0.42
KDM4E B2RXH2 1/20 0.42
RECQL P46063 1/20 0.41
TSHR P16473 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL6746212 0.81 ALDH1A1 (0.48) CA12CA9PTGESALOX5C5AR1
SCHEMBL11034530 0.76 APOBEC3G (0.50) CA12CA9KEAP1NFE2L2TAS2R14
SCHEMBL1878018 0.75 CA12 (0.58) CA12CA9C5AR1KEAP1NFE2L2
SCHEMBL28878524 0.73 ALDH1A1 (0.52) CA12CA9C5AR1KEAP1NFE2L2
SCHEMBL9487894 0.72 CA12 (0.58) CA12CA9PTGESC5AR1KEAP1
SCHEMBL28244533 0.72 KMT2A (0.63) CA12CA9KEAP1NFE2L2ALDH1A1
SCHEMBL31195348 0.72 ALDH1A1 (0.50) CA12CA9ALOX5C5AR1KEAP1
SCHEMBL9316022 0.72 MEN1 (0.56) CA12CA9C5AR1KEAP1NFE2L2
SCHEMBL8356839 0.72 ALDH1A1 (0.50) CA12CA9C5AR1KEAP1NFE2L2
SCHEMBL27792785 0.72 ALDH1A1 (0.50) CA12CA9C5AR1KEAP1NFE2L2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1040933-B1 Double-side recording medium OJI PAPER CO (JP) 2004-03-03 EP disclosed
EP-1040933-A1 Double-side recording medium OJI PAPER CO., LTD. (JP) 2000-10-04 EP disclosed