SCHEMBL6741607

SCHEMBL6741607

O=C(O)Cc1ccc(O)c2ccccc12

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 2/20 0.61
TDP1 Q9NUW8 2/20 0.58
KDM4E B2RXH2 3/20 0.53
GAA P10253 2/20 0.53
HPGD P15428 2/20 0.53
HSD17B10 Q99714 2/20 0.53
ALDH1A1 P00352 1/20 0.53
GLA P06280 1/20 0.53
IDO1 P14902 2/20 0.52
CAMK2A Q9UQM7 1/20 0.44
RGS12 O14924 1/20 0.42
LMNA P02545 1/20 0.42
POLB P06746 1/20 0.42
MAPT P10636 1/20 0.42
TSHR P16473 1/20 0.42
NFKB1 P19838 1/20 0.42
APEX1 P27695 1/20 0.42
THPO P40225 1/20 0.42
BLM P54132 1/20 0.42
GNAI1 P63096 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL69027 0.89 TDP1 (0.69) AKR1B1TDP1KDM4EGAAHPGD
SCHEMBL29732929 0.89 TDP1 (0.69) AKR1B1TDP1KDM4EGAAHPGD
SCHEMBL6738986 0.88 AKR1B1 (0.67) AKR1B1TDP1KDM4EGAAHPGD
SCHEMBL17451249 0.86 IDO1 (0.54) AKR1B1TDP1KDM4EGAAHPGD
SCHEMBL21585561 0.83 TDP1 (0.62) AKR1B1TDP1KDM4EGAAHPGD
SCHEMBL2192625 0.82 IDO1 (0.45) AKR1B1TDP1KDM4EGAAHPGD
SCHEMBL31604997 0.82 IDO1 (0.45) AKR1B1TDP1KDM4EGAAHPGD
SCHEMBL69234 0.81 TDP1 (0.76) AKR1B1TDP1KDM4EHPGDGLA
SCHEMBL29564952 0.81 TDP1 (0.76) AKR1B1TDP1KDM4EHPGDGLA
SCHEMBL17537567 0.78 TDP1 (0.56) AKR1B1TDP1HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109970921-B High-water-reduction low-sensitivity polycarboxylate superplasticizer and preparation method thereof 科之杰新材料集团有限公司 2020-07-03 CN claimed
WO-2019233215-A1 HIGH WATER-REDUCING AND LOW SENSITIVITY POLYCARBOXYLATE SUPERPLASTICIZER AND PREPARATION METHOD THEREFOR 科之杰新材料集团有限公司 (CN) 2019-12-12 WO claimed
US-20040086983-A1 Method for producing a heterocyclic compound and an aromatic carboxylic acid having one or more hydroxyl groups, and modified aromatic ring dioxygenase MARINE BIOTHECHNOLOGY INSTITUTE., LTD. (JP) 2004-05-06 US claimed
CN-109970921-B High-water-reduction low-sensitivity polycarboxylate superplasticizer and preparation method thereof 科之杰新材料集团有限公司 2020-07-03 CN disclosed
WO-2019233215-A1 HIGH WATER-REDUCING AND LOW SENSITIVITY POLYCARBOXYLATE SUPERPLASTICIZER AND PREPARATION METHOD THEREFOR 科之杰新材料集团有限公司 (CN) 2019-12-12 WO disclosed
US-20040086983-A1 Method for producing a heterocyclic compound and an aromatic carboxylic acid having one or more hydroxyl groups, and modified aromatic ring dioxygenase MARINE BIOTHECHNOLOGY INSTITUTE., LTD. (JP) 2004-05-06 US disclosed