Demeton-S-Methyl

Demeton-S-Methyl

SCHEMBL6741750

CCSCCSP(=O)(OC)OC.CCSCCSP(=O)(OC)OC

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.52
MAPK1 P28482 1/20 0.52
ALDH1A1 P00352 2/20 0.45
CYP3A4 P08684 2/20 0.45
HSD17B10 Q99714 1/20 0.45
TDP1 Q9NUW8 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TSHR P16473 2/20 0.31
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Demeton-S-Methyl SCHEMBL73358 1.00 MAPT (0.52) MAPTMAPK1ALDH1A1CYP3A4HSD17B10
Demeton-S-Methyl SCHEMBL5917224 0.83 MEN1 (0.53) MAPTMAPK1ALDH1A1CYP3A4HSD17B10
Demeton S SCHEMBL117918 0.80 ALDH1A1 (0.59) ALDH1A1CYP3A4HSD17B10TDP1MEN1
Demeton S SCHEMBL6732303 0.80 ALDH1A1 (0.59) ALDH1A1CYP3A4HSD17B10TDP1MEN1
SCHEMBL2180857 0.78 ALDH1A1 (0.47) MAPTMAPK1ALDH1A1CYP3A4HSD17B10
SCHEMBL11855753 0.78 ALDH1A1 (0.42) MAPTMAPK1ALDH1A1CYP3A4HSD17B10
SCHEMBL1359029 0.78
SCHEMBL117916 0.76 MAPT (0.50) MAPTMAPK1
Demeton S SCHEMBL6047148 0.74 MEN1 (0.57) MAPTMAPK1ALDH1A1CYP3A4HSD17B10
Demeton S SCHEMBL20544186 0.74 ALDH1A1 (0.52) ALDH1A1CYP3A4HSD17B10TDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6680065-B2 FOR TREATMENT OF WOODY PLANTS; EMPLOYED IN HOLLOW PREFORMED IN THE WOODY PLANT BAYER AKTIENGESELLSCHAFT (DE) 2004-01-20 US disclosed
US-6528079-B2 For treatment of woody plants; employed in a hollow preformed in the woody plant BAYER AKTIENGESELLSCHAFT (DE) 2003-03-04 US disclosed
US-20020061323-A1 SHAPED BODIES WHICH RELEASE AGROCHEMICAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2002-05-23 US disclosed
US-20010039248-A1 Shaped bodies which release agrochemical active substances PODSZUN WOLFGANG (DE) 2001-11-08 US disclosed
EP-0564945-B1 A method of controlling harmful insects BAYER AGROCHEM KK (JP) 2001-01-24 EP disclosed
US-6063393-A RODS OR PINS TO BE PRESSED INTO PLANTS NIHON BAYER AGROCHEM K.K. (JP) 2000-05-16 US disclosed
EP-0564945-A1 A method of controlling harmful insects NIHON BAYER AGROCHEM K.K. (JP) 1993-10-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020061323-A1 SHAPED BODIES WHICH RELEASE AGROCHEMICAL ACTIVE SUBSTANCES AGL, CHMP4B, GUSB MAPT 1236/4885MAPK1 4581/4885ALDH1A1 729/4885
US-20010039248-A1 Shaped bodies which release agrochemical active substances AGL, CHMP4B, GUSB MAPT 1193/4885MAPK1 4549/4885ALDH1A1 758/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.