SCHEMBL6741919

SCHEMBL6741919

CN1CCCC1=CC=C1C(=O)N(C)C(=S)N1C

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 14/20 1.00
MEN1 O00255 13/20 1.00
KMT2A Q03164 13/20 1.00
ALDH1A1 P00352 12/20 1.00
RAB9A P51151 8/20 1.00
SMN1; SMN2 Q16637 6/20 1.00
GAA P10253 4/20 1.00
PSMD14 O00487 2/20 1.00
NPC1 O15118 6/20 0.56
MAPK1 P28482 4/20 0.56
LMNA P02545 3/20 0.56
IDE P14735 2/20 0.50
KDM4E B2RXH2 1/20 0.50
USP2 O75604 1/20 0.49
BRD4 O60885 1/20 0.40
BRD2 P25440 1/20 0.40
POLB P06746 3/20 0.39
TNNI3 P19429 1/20 0.39
TNNT2 P45379 1/20 0.39
TNNC1 P63316 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6741916 1.00 MAPT (1.00) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL13026074 1.00 MAPT (1.00) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL19240048 0.84 MEN1 (0.72) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL19240078 0.81 MEN1 (0.68) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL19240083 0.73 MEN1 (0.56) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL19240014 0.73 MAPT (0.60) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL14269386 0.72 KMT2A (0.56) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL2058993 0.72 KMT2A (0.56) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL2058995 0.72 KMT2A (0.56) MAPTMEN1KMT2AALDH1A1RAB9A
SCHEMBL19240087 0.72 MAPT (0.56) MAPTMEN1KMT2AALDH1A1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040196778-A1 Digital optical data carrier in disc format DIERKS DIETER (DE) 2004-10-07 US claimed