SCHEMBL2058995

SCHEMBL2058995

CN1CCCC1=CC=C1C(=O)N(C)C(=O)N(C)C1=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 8/20 0.56
MAPT P10636 8/20 0.56
MEN1 O00255 7/20 0.56
ALDH1A1 P00352 5/20 0.56
GAA P10253 3/20 0.56
RAB9A P51151 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
PSMD14 O00487 2/20 0.56
IDE P14735 2/20 0.47
KDM4E B2RXH2 2/20 0.47
NPC1 O15118 1/20 0.47
USP2 O75604 1/20 0.46
LMNA P02545 1/20 0.46
BRD4 O60885 1/20 0.44
BRD2 P25440 1/20 0.44
RECQL P46063 1/20 0.38
KDM4C Q9H3R0 1/20 0.38
APP P05067 1/20 0.33
POLB P06746 1/20 0.33
PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14269386 1.00 KMT2A (0.56) KMT2AMAPTMEN1ALDH1A1GAA
SCHEMBL2058993 1.00 KMT2A (0.56) KMT2AMAPTMEN1ALDH1A1GAA
SCHEMBL19240048 0.85 MEN1 (0.72) KMT2AMAPTMEN1ALDH1A1GAA
SCHEMBL19240011 0.81 MEN1 (0.59) KMT2AMAPTMEN1ALDH1A1GAA
SCHEMBL25477347 0.77 MEN1 (0.46) KMT2AMAPTMEN1ALDH1A1GAA
SCHEMBL5425916 0.75 MEN1 (0.64) KMT2AMAPTMEN1ALDH1A1GAA
SCHEMBL14489574 0.75 MEN1 (0.64) KMT2AMAPTMEN1ALDH1A1GAA
SCHEMBL19038901 0.73 ALDH1A1 (0.47) KMT2AMAPTMEN1ALDH1A1GAA
SCHEMBL19038912 0.73 ALDH1A1 (0.47) KMT2AMAPTMEN1ALDH1A1GAA
SCHEMBL19240010 0.73 ALDH1A1 (0.47) KMT2AMAPTMEN1ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7968166-B2 Optical recording system HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2011-06-28 US disclosed
EP-1984920-B1 OPTICAL RECORDING SYSTEM HEWLETT PACKARD DEVELOPMENT CO (US) 2010-04-28 EP disclosed
US-20070179057-A1 OPTICAL RECORDING SYSTEM HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2007-08-02 US disclosed