SCHEMBL674203

SCHEMBL674203

Brc1cccc(Br)c1Br.C(OCC1CO1)C1CO1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
TSHR P16473 5/20 0.47
TP53 P04637 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.47
HIF1A Q16665 2/20 0.47
CYP3A4 P08684 1/20 0.47
TDP1 Q9NUW8 2/20 0.44
GLA P06280 1/20 0.41
MAPK1 P28482 1/20 0.38
MEN1 O00255 3/20 0.35
KMT2A Q03164 3/20 0.35
MAPT P10636 2/20 0.35
HPGD P15428 2/20 0.35
CYP1A2 P05177 1/20 0.35
PPARG P37231 1/20 0.35
LMNA P02545 1/20 0.35
GAA P10253 1/20 0.35
PKM P14618 1/20 0.35
PRMT5 O14744 1/20 0.34
WDR77 Q9BQA1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28401885 0.91 ALDH1A1 (0.49) ALDH1A1TSHRTP53SMN1; SMN2HIF1A
SCHEMBL1565563 0.88 TDP1 (0.52) ALDH1A1TSHRTP53SMN1; SMN2HIF1A
SCHEMBL2234957 0.88 TSHR (0.41) ALDH1A1TSHRTP53SMN1; SMN2HIF1A
SCHEMBL3885637 0.88 TSHR (0.41) ALDH1A1TSHRTP53SMN1; SMN2HIF1A
SCHEMBL3681261 0.85 TSHR (0.44) ALDH1A1TSHRTP53SMN1; SMN2HIF1A
SCHEMBL11219769 0.84 ALDH1A1 (0.41) ALDH1A1TSHRTP53SMN1; SMN2HIF1A
SCHEMBL10613835 0.84 ALDH1A1 (0.38) ALDH1A1TSHRTP53SMN1; SMN2HIF1A
SCHEMBL8523339 0.81 ALDH1A1 (0.52) ALDH1A1TSHRTP53SMN1; SMN2HIF1A
SCHEMBL372166 0.80 ALDH1A1 (0.57) ALDH1A1TSHRTP53SMN1; SMN2HIF1A
SCHEMBL27432297 0.79 TSHR (0.48) ALDH1A1TSHRTP53SMN1; SMN2HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8067497-B2 Flame-retardant for engineering thermoplastic applications BROMINE COMPOUNDS LTD. (IL) 2011-11-29 US claimed
EP-1587865-B1 FLAME-RETARDANT FOR ENGINEERING THERMOPLASTIC APPLICATIONS BROMINE COMPOUNDS LTD (IL) 2006-09-13 EP claimed
US-20060148948-A1 Flame-retardant for engineering thermoplastic applications BROMINE COMPOUNDS LTD. (IL) 2006-07-06 US claimed
JP-2006515035-A 2006-05-18 JP claimed
EP-1587865-A1 FLAME-RETARDANT FOR ENGINEERING THERMOPLASTIC APPLICATIONS Bromine Compounds Ltd. (IL) 2005-10-26 EP claimed
WO-2004063263-A1 FLAME-RETARDANT FOR ENGINEERING THERMOPLASTIC APPLICATIONS BROMINE COMPOUNDS LTD. (IL) 2004-07-29 WO claimed
US-20250313657-A1 Furan Moiety-Containing Olefin Copolymer and Reversible Crosslinked or Functionalized Olefin Copolymer EXXONMOBIL TECHNOLOGY & ENGINEERING COMPANY (US) 2025-10-09 US disclosed
CN-102731825-B Chloro- and bromo-containing silicate flame retardant compound and preparation method thereof USTC UNIV SCIENCE TECH CN 2013-07-17 CN disclosed
CN-102731825-A Chloro- and bromo-containing silicate flame retardant compound and preparation method thereof USTC UNIV SCIENCE TECH CN 2012-10-17 CN disclosed
US-8067497-B2 Flame-retardant for engineering thermoplastic applications BROMINE COMPOUNDS LTD. (IL) 2011-11-29 US disclosed
EP-1712593-B1 FLAME-RETARDANT POLYAMIDE COMPOSITION AND USE THEREOF MITSUI CHEMICALS INC (JP) 2011-08-10 EP disclosed
US-20070267607-A1 Flame-Retardant Polyamide Composition and Use Thereof MITSUI CHEMICALS, INC. (JP) 2007-11-22 US disclosed
EP-1712593-A1 FLAME-RETARDANT POLYAMIDE COMPOSITION AND USE THEREOF Mitsui Chemicals, Inc. (JP) 2006-10-18 EP disclosed
EP-1587865-B1 FLAME-RETARDANT FOR ENGINEERING THERMOPLASTIC APPLICATIONS BROMINE COMPOUNDS LTD (IL) 2006-09-13 EP disclosed
US-20060148948-A1 Flame-retardant for engineering thermoplastic applications BROMINE COMPOUNDS LTD. (IL) 2006-07-06 US disclosed
EP-1587865-A1 FLAME-RETARDANT FOR ENGINEERING THERMOPLASTIC APPLICATIONS Bromine Compounds Ltd. (IL) 2005-10-26 EP disclosed
WO-2004063263-A1 FLAME-RETARDANT FOR ENGINEERING THERMOPLASTIC APPLICATIONS BROMINE COMPOUNDS LTD. (IL) 2004-07-29 WO disclosed
EP-1026189-B1 THERMOPLASTIC DICYCLOPENTADIENE-BASE OPEN-RING POLYMERS, HYDROGENATED DERIVATIVES THEREOF, AND PROCESSES FOR THE PREPARATION OF BOTH NIPPON ZEON CO (JP) 2004-01-02 EP disclosed
US-6511756-B1 Impact resistance; chemical and weather resistance; flexible; transparent; carport and housing exteriors, food packaging films, optical lenses, electrical wiring and power cable wrapping NIPPON ZEON CO., LTD. (JP) 2003-01-28 US disclosed
EP-1026189-A1 THERMOPLASTIC DICYCLOPENTADIENE-BASE OPEN-RING POLYMERS, HYDROGENATED DERIVATIVES THEREOF, AND PROCESSES FOR THE PREPARATION OF BOTH Nippon Zeon Co., Ltd. (JP) 2000-08-09 EP disclosed