Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | PPARA | Q07869 | 2/20 | 0.51 |
| ▸ | TTR | P02766 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.51 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.51 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9213101 | 1.00 | TSHR (0.58) | TSHRTDP1CYP2C9PPARATTR | |
| SCHEMBL7639935 | 0.98 | TSHR (0.60) | TSHRTDP1CYP2C9PPARATTR | |
| SCHEMBL5223212 | 0.93 | TSHR (0.62) | TSHRTDP1CYP2C9PPARATTR | |
| SCHEMBL6743557 | 0.87 | TSHR (0.59) | TSHRTDP1CYP2C9PPARATTR | |
| SCHEMBL5266458 | 0.85 | TSHR (0.70) | TSHRTDP1CYP2C9PPARATTR | |
| SCHEMBL4102060 | 0.84 | TSHR (0.60) | TSHRTDP1CYP2C9PPARATTR | |
| SCHEMBL6738557 | 0.84 | TSHR (0.60) | TSHRTDP1CYP2C9PPARATTR | |
| SCHEMBL822786 | 0.84 | TSHR (0.60) | TSHRTDP1CYP2C9PPARATTR | |
| SCHEMBL13475550 | 0.84 | TSHR (0.60) | TSHRTDP1CYP2C9PPARATTR | |
| SCHEMBL2712500 | 0.84 | TSHR (0.60) | TSHRTDP1CYP2C9PPARATTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6693158-B2 | ORGANONITROGEN, ORGANOOXYGEN POLYMER | NATIONAL SCIENCE COUNCIL (TW) | 2004-02-17 | — | — | US | disclosed |
| US-20030109656-A1 | Electroluminiscent conjugated polymers modified with high eletronegative heterocyclic moieties and their applications in polymeric light emitting diodes | NATIONAL SCIENCE COUNCIL TAIWAN CORPORATION (TW) | 2003-06-12 | — | — | US | disclosed |
| US-6495644-B1 | CONTAINING HETEROCYCLIC GROUPS SUCH AS 1,3,4-OXADIAZOLE-DIYL, 1,3,4-THIADIAZOLE-DIYL AND 1,2,4-TRIAZOLE-DIYL; HIGH EXTERNAL QUANTUM EFFICIENCY | NATIONAL SCIENCE COUNCIL (TW) | 2002-12-17 | — | — | US | disclosed |