Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 7/20 | 0.49 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4193694 | 0.85 | MME (0.55) | MMETGFBR1CYP2C9CA2CA1 | |
| SCHEMBL2633143 | 0.85 | MME (0.55) | MMETGFBR1CYP2C9CA2CA1 | |
| SCHEMBL27088409 | 0.85 | MME (0.55) | MMETGFBR1CYP2C9CA2CA1 | |
| SCHEMBL16317817 | 0.76 | MME (0.43) | MMETGFBR1CYP2C9ACEPIN1 | |
| SCHEMBL6138128 | 0.73 | MME (0.59) | MMETGFBR1ACECA2 | |
| SCHEMBL9650023 | 0.72 | MME (0.58) | MMETGFBR1ACEECE1 | |
| SCHEMBL13380098 | 0.72 | MME (0.58) | MMETGFBR1ACEECE1 | |
| SCHEMBL14163011 | 0.72 | MME (0.58) | MMETGFBR1ACEECE1 | |
| SCHEMBL31501278 | 0.72 | CYP2C9 (0.45) | TGFBR1CYP2C9PIN1 | |
| SCHEMBL16314051 | 0.71 | MME (0.56) | MMETGFBR1CYP2C9ACEECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8182829-B2 | Drug eluting implantable medical device with hemocompatible and/or prohealing topcoat | ABBOTT CARDIOVASCULAR SYSTEMS INC. (US) | 2012-05-22 | — | — | US | disclosed |