Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 5/20 | 0.55 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.53 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 4/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4193694 | 1.00 | MME (0.55) | MMETGFBR1CYP2C9CA2CA4 | |
| SCHEMBL2633143 | 1.00 | MME (0.55) | MMETGFBR1CYP2C9CA2CA4 | |
| SCHEMBL6742503 | 0.85 | MME (0.49) | MMETGFBR1CYP2C9CA2PIN1 | |
| SCHEMBL2081023 | 0.84 | CYP2C9 (0.46) | MMETGFBR1CYP2C9CA2CA4 | |
| SCHEMBL1912625 | 0.84 | CYP2C9 (0.46) | MMETGFBR1CYP2C9CA2CA4 | |
| SCHEMBL5821359 | 0.83 | MME (0.51) | MMETGFBR1CA2NOD1CA1 | |
| SCHEMBL9651941 | 0.83 | MME (0.51) | MMETGFBR1CA2NOD1CA1 | |
| SCHEMBL3498364 | 0.83 | NOD1 (0.46) | MMETGFBR1CYP2C9CA2CA4 | |
| SCHEMBL21314174 | 0.83 | MME (0.51) | MMETGFBR1CA2NOD1CA1 | |
| SCHEMBL3498357 | 0.83 | NOD1 (0.46) | MMETGFBR1CYP2C9CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4319795-A1 | PERFORMANCE-ENHANCING EXCIPIENTS AND METHODS OF REDUCING VISCOSITY AND INCREASING STABILITY OF BIOLOGIC FORMULATIONS | Avantor Performance Materials, LLC (US) | 2024-02-14 | — | — | EP | disclosed |
| CN-117355321-A | Performance enhancing excipients and methods for reducing viscosity and improving stability of biological agents | 安万托特性材料股份有限公司 | 2024-01-05 | — | — | CN | disclosed |