Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 13/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11196330 | 0.81 | SIRT2 (0.40) | SIRT2CYP19A1ALOX5 | |
| SCHEMBL28210989 | 0.77 | CYP1A2 (0.40) | — | |
| SCHEMBL6570244 | 0.76 | SIRT2 (0.44) | SIRT2CYP19A1HSD17B10 | |
| SCHEMBL15657556 | 0.75 | KDM4E (0.36) | — | |
| SCHEMBL6535095 | 0.75 | PTPN1 (0.33) | — | |
| SCHEMBL573648 | 0.75 | SIRT2 (0.40) | SIRT2CYP19A1 | |
| SCHEMBL8622095 | 0.73 | SIRT2 (0.45) | SIRT2CYP19A1ALOX5 | |
| SCHEMBL10959932 | 0.73 | SIRT2 (0.41) | SIRT2CYP19A1ALOX5 | |
| SCHEMBL9974498 | 0.73 | KDM4E (0.34) | HSD17B10 | |
| SCHEMBL11884442 | 0.72 | SIRT2 (0.37) | SIRT2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2004137228-A | METHOD FOR PRODUCING 2-SUBSTITUTED-4-OXO-4, 5, 6, 7-TETRAHYDROINDOLE COMPOUND | NIPPON ZEON CO LTD | 2004-05-13 | — | — | JP | disclosed |