Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 4/20 | 0.38 |
| ▸ | MMP9 | P14780 | 4/20 | 0.38 |
| ▸ | MMP8 | P22894 | 4/20 | 0.38 |
| ▸ | MMP13 | P45452 | 4/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 10/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10959932 | 0.92 | SIRT2 (0.41) | SIRT2MMP2MMP9MMP8MMP13 | |
| SCHEMBL10187814 | 0.91 | MMP2 (0.40) | SIRT2MMP2MMP9MMP8MMP13 | |
| SCHEMBL6742601 | 0.81 | SIRT2 (0.39) | SIRT2CYP19A1ALOX5 | |
| SCHEMBL8622095 | 0.75 | SIRT2 (0.45) | SIRT2CYP19A1ALOX5 | |
| SCHEMBL11884442 | 0.74 | SIRT2 (0.37) | SIRT2CYP19A1 | |
| SCHEMBL15659217 | 0.74 | LMNA (0.40) | — | |
| SCHEMBL3682825 | 0.74 | MMP2 (0.43) | MMP2MMP9MMP8MMP13 | |
| SCHEMBL8622131 | 0.74 | SIRT2 (0.41) | SIRT2CYP19A1 | |
| SCHEMBL8621156 | 0.74 | SIRT2 (0.47) | SIRT2CYP19A1ALOX5 | |
| SCHEMBL6570244 | 0.74 | SIRT2 (0.44) | SIRT2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0095330-A1 | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1983-11-30 | — | — | EP | disclosed |