Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 8/20 | 0.60 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.57 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | GALR3 | O60755 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6742906 | 1.00 | ADRB3 (0.60) | ADRB3ADRB2LMNAHIF1ASLC6A2 | |
| SCHEMBL7111823 | 1.00 | ADRB3 (0.60) | ADRB3ADRB2LMNAHIF1ASLC6A2 | |
| SCHEMBL7109801 | 0.89 | ADRB3 (0.61) | ADRB3ADRB2LMNAHIF1ASLC6A2 | |
| SCHEMBL6743689 | 0.89 | ADRB3 (0.61) | ADRB3ADRB2LMNAHIF1ASLC6A2 | |
| SCHEMBL6743683 | 0.89 | ADRB3 (0.61) | ADRB3ADRB2LMNAHIF1ASLC6A2 | |
| SCHEMBL6743614 | 0.89 | ADRB3 (0.72) | ADRB3ADRB2LMNAHIF1ASLC6A2 | |
| SCHEMBL6743617 | 0.89 | ADRB3 (0.72) | ADRB3ADRB2LMNAHIF1ASLC6A2 | |
| SCHEMBL6742500 | 0.84 | ADRB2 (0.67) | ADRB3ADRB2LMNAHIF1ASLC6A2 | |
| SCHEMBL6742504 | 0.84 | ADRB2 (0.67) | ADRB3ADRB2LMNAHIF1ASLC6A2 | |
| SCHEMBL6814003 | 0.84 | ADRB3 (0.80) | ADRB3ADRB2LMNAHIF1ASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1072583-B1 | 2-METHYLPROPIONIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | KISSEI PHARMACEUTICAL (JP) | 2004-09-01 | — | — | EP | disclosed |
| US-6696489-B1 | PHENOLIC AND PHENYLAMINO SUBSTITUENTS; BETA 3-ADRENOCEPTOR AGONISTS; OBESITY, HYPERGLYCEMIA, INTESTINAL HYPERMOTILITY, POLLAKIURIA, URINARY INCONTINENCE, DEPRESSION | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2004-02-24 | — | — | US | disclosed |
| EP-1072583-A1 | 2-METHYLPROPIONIC ACID DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Kissei Pharmaceutical Co., Ltd. (JP) | 2001-01-31 | — | — | EP | disclosed |