SCHEMBL6742968

SCHEMBL6742968

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CCC4CC(OC(=O)c5ccccc5)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.72

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CDC25A P30304 4/20 0.72
POLA1 P09884 1/20 0.69
VDR P11473 3/20 0.61
USP2 O75604 1/20 0.61
CYP2D6 P10635 1/20 0.58
CYP2C19 P33261 1/20 0.58
ST6GAL1 P15907 1/20 0.57
INPP5D Q92835 1/20 0.57
ABCC4 O15439 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10298005 1.00 CDC25A (0.72) CDC25APOLA1VDRUSP2CYP2D6
SCHEMBL6742962 1.00 CDC25A (0.72) CDC25APOLA1VDRUSP2CYP2D6
SCHEMBL13412384 0.92 CDC25A (0.67) CDC25APOLA1VDRUSP2CYP2D6
SCHEMBL8918931 0.92 CDC25A (0.67) CDC25APOLA1VDRUSP2CYP2D6
SCHEMBL8918935 0.92 CDC25A (0.67) CDC25APOLA1VDRUSP2CYP2D6
SCHEMBL10425455 0.92 CDC25A (0.66) CDC25APOLA1VDRUSP2CYP2D6
SCHEMBL10425289 0.90 CDC25A (0.62) CDC25APOLA1VDRUSP2CYP2D6
SCHEMBL11146732 0.90 CDC25A (0.72) CDC25APOLA1VDRUSP2CYP2D6
SCHEMBL8837072 0.90 VDR (0.61) CDC25APOLA1VDRUSP2ST6GAL1
SCHEMBL14007471 0.89 CDC25A (0.59) CDC25APOLA1VDRUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030157158-A1 Enhanced liposomal thioretinaco ozonide compositions and liposomal carrier MCCULLY KILMER S (US) 2003-08-21 US claimed
WO-2003057192-A1 ENHANCED LIPOSOMAL THIORETINACO OZONIDE COMPOSITIONS AND LIPOSOMAL CARRIER MCCULLY KILMER S (US) 2003-07-17 WO claimed
US-6696082-B2 COMPLEX COMPRISING N-HOMOCYSTEINE THIOLACTONYL RETINAMIDE, COBALAMIN, OZONE, OXYGEN, AND ADENOSINE TRIPHOSPHATE; ANTICARCINGENIC, ANTITUMOR, AND VIRICIDAL AGENTS; ATHEROSCLEROSIS PREVENTION; AGING RESISTANCE MCCULLY KILMER S (US) 2004-02-24 US disclosed
US-20030157158-A1 Enhanced liposomal thioretinaco ozonide compositions and liposomal carrier MCCULLY KILMER S (US) 2003-08-21 US disclosed
WO-2003057192-A1 ENHANCED LIPOSOMAL THIORETINACO OZONIDE COMPOSITIONS AND LIPOSOMAL CARRIER MCCULLY KILMER S (US) 2003-07-17 WO disclosed
US-6274118-B1 INJECTING PATIENT HAVING ENDOCRINE CANCER IN NON-PROSTATIC TISSUE WITH BIOLOGICAL BINDING UNITS WHICH BIND TO PROSTATE SPECIFIC ANTIGEN PRODUCED BY NON-PROSTATIC TISSUE NORDION INTERNATIONAL INC. (CA) 2001-08-14 US disclosed
US-5688780-A ANTICHOLESTEROL AGENTS, CHOLESTEROL BIOSYNTHESIS INHIBITION SRI INTERNATIONAL (US) 1997-11-18 US disclosed
US-5510340-A OXYSTEROL ANALOGS SRI INTERNATIONAL (US) 1996-04-23 US disclosed
WO-1995002424-A1 LOCALIZATION AND THERAPY OF NON-PROSTATIC ENDOCRINE CANCER WITH AGENTS DIRECTED AGAINST PROSTATE SPECIFIC ANTIGEN NORDION INTERNATIONAL INC. (CA) 1995-01-26 WO disclosed
US-4684479-A Surfactant mixtures, stable gas-in-liquid emulsions, and methods for the production of such emulsions from said mixtures CAVITATION-CONTROL TECHNOLOGY, INC. 1987-08-04 US disclosed