Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | MC4R | P32245 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | DRD4 | P21917 | 1/20 | 0.56 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21141857 | 0.93 | MC4R (0.77) | SIGMAR1KMT2AKDM4EMEN1MC4R | |
| SCHEMBL14407770 | 0.89 | SIGMAR1 (0.69) | SIGMAR1KMT2AKDM4EMEN1MC4R | |
| SCHEMBL278653 | 0.89 | SIGMAR1 (0.69) | SIGMAR1KMT2AKDM4EMEN1MC4R | |
| SCHEMBL11611819 | 0.87 | SIGMAR1 (0.67) | SIGMAR1KMT2AKDM4EMEN1MC4R | |
| SCHEMBL18712996 | 0.85 | SIGMAR1 (0.64) | SIGMAR1KMT2AKDM4EMEN1MC4R | |
| SCHEMBL3260289 | 0.85 | SIGMAR1 (0.64) | SIGMAR1KMT2AKDM4EMEN1MC4R | |
| SCHEMBL16226702 | 0.84 | CYP2D6 (0.69) | SIGMAR1KMT2AKDM4EMEN1MC4R | |
| SCHEMBL16226120 | 0.84 | CYP2D6 (0.69) | SIGMAR1KMT2AKDM4EMEN1MC4R | |
| SCHEMBL13638129 | 0.84 | KMT2A (0.71) | SIGMAR1KMT2AKDM4EMEN1MC4R | |
| SCHEMBL16226234 | 0.84 | KMT2A (0.71) | SIGMAR1KMT2AKDM4EMEN1MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6689919-B1 | SOLUBLE POLY(OXYFLUOROPHENYLENE) COMPOUNDS WITH EXCELLENT HEAT RESISTANCE, MEMBRANE-FORMABILITY AND CHEMICAL STABILITY | JAPAN SCIENCE AND TECHNOLOGY CORPORATION (JP) | 2004-02-10 | — | — | US | disclosed |