Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | F12 | P00748 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL646712 | 1.00 | MAOA (0.43) | MAOAMAOBCES1ALDH1A1CES2 | |
| SCHEMBL646713 | 1.00 | MAOA (0.43) | MAOAMAOBCES1ALDH1A1CES2 | |
| SCHEMBL19074281 | 0.78 | BCL2L1 (0.36) | PTPN1GSK3BPOLBMAPTHSD17B10 | |
| SCHEMBL19074310 | 0.78 | BCL2L1 (0.36) | PTPN1GSK3BPOLBMAPTHSD17B10 | |
| SCHEMBL11309464 | 0.78 | CES1 (0.39) | CES1ALDH1A1CES2TSHRDAO | |
| SCHEMBL19056959 | 0.78 | BCL2L1 (0.36) | PTPN1GSK3BPOLBMAPTHSD17B10 | |
| SCHEMBL19056958 | 0.78 | BCL2L1 (0.36) | PTPN1GSK3BPOLBMAPTHSD17B10 | |
| SCHEMBL16933937 | 0.78 | CES1 (0.39) | CES1ALDH1A1CES2TSHRDAO | |
| SCHEMBL11309461 | 0.78 | CES1 (0.39) | CES1ALDH1A1CES2TSHRDAO | |
| SCHEMBL17230462 | 0.76 | CES1 (0.43) | CES1ALDH1A1CES2TSHRDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11667840-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2023-06-06 | — | — | US | disclosed |
| US-20190330530-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2019-10-31 | — | — | US | disclosed |
| US-20040209897-A1 | Mitogen activated protein kinase-activated protein kinase-2 inhibiting compounds | PHARMACIA CORPORATION | 2004-10-21 | — | — | US | disclosed |
| US-5313001-A | Reacting a halogenated aromatic compound with a 1,1-difluoro ethylene compound in presence of palladium catalyst | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040209897-A1 | Mitogen activated protein kinase-activated protein kinase-2 inhibiting compounds | MAPKAPK2, MAP3K2, MKNK2 | MAOA 2157/4885MAOB 1951/4885CES1 4321/4885 |
| US-11667840-B2 | Liquid-crystalline medium | FES, BLM, CXCL12 | MAOA 2081/4885MAOB 1750/4885CES1 4110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.