Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.39 |
| ▸ | CBFB | Q13951 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 2/20 | 0.38 |
| ▸ | BCR | P11274 | 2/20 | 0.38 |
| ▸ | ALOX5AP | P20292 | 6/20 | 0.38 |
| ▸ | FEN1 | P39748 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6749848 | 0.89 | PTGES2 (0.44) | TRPV1CBFBALOX5APFEN1CTSD | |
| SCHEMBL6726003 | 0.88 | PTGS2 (0.41) | PTGS2TRPV1SCN9ACBFBABL1 | |
| SCHEMBL6750087 | 0.85 | ALOX5AP (0.47) | TRPV1ALOX5APFEN1 | |
| SCHEMBL6749919 | 0.85 | PTGS2 (0.47) | PTGS2ALOX5APFEN1PTGS1CA1 | |
| SCHEMBL6838993 | 0.85 | PTGS2 (0.48) | PTGS2ABL1BCRPTGS1CA1 | |
| SCHEMBL6745515 | 0.85 | ALOX5AP (0.38) | PTGS2SCN9AALOX5APFEN1PTGS1 | |
| SCHEMBL6747090 | 0.85 | PTGS2 (0.42) | PTGS2TRPV1SCN9AALOX5APFEN1 | |
| SCHEMBL6750040 | 0.84 | PTGS2 (0.46) | PTGS2ALOX5APFEN1ALDH1A1PTGS1 | |
| SCHEMBL6749867 | 0.83 | PTGS2 (0.49) | PTGS2ALOX5APFEN1PTGS1CA1 | |
| SCHEMBL6746716 | 0.83 | PTGS2 (0.43) | PTGS2ALOX5APFEN1NPC1PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | claimed |
| US-6699884-B2 | ANTIINFLAMMATORY CYCLOOXYGENASE INHIBITORS. | PHARMACIA CORPORATION | 2004-03-02 | — | — | US | disclosed |