Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.50 |
| ▸ | UQCRB | P14927 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 3/20 | 0.43 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | PAK4 | O96013 | 1/20 | 0.43 |
| ▸ | PIM1 | P11309 | 1/20 | 0.43 |
| ▸ | LTK | P29376 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6701816 | 0.85 | HSD17B2 (0.54) | HSD17B2KMT2APKMUQCRBMAPT | |
| SCHEMBL6702193 | 0.84 | UQCRB (0.51) | HSD17B2KMT2APKMUQCRBMAPT | |
| SCHEMBL6704050 | 0.84 | AURKB (0.59) | HSD17B2KMT2APKMUQCRBMAPT | |
| SCHEMBL6702181 | 0.84 | HSD17B2 (0.58) | HSD17B2KMT2APKMUQCRBMAPT | |
| SCHEMBL6703748 | 0.81 | AURKB (0.59) | HSD17B2KMT2APKMUQCRBMAPT | |
| SCHEMBL6703746 | 0.81 | AURKB (0.59) | HSD17B2KMT2APKMUQCRBMAPT | |
| SCHEMBL6704528 | 0.81 | AURKB (0.59) | HSD17B2KMT2APKMUQCRBMAPT | |
| SCHEMBL6703763 | 0.81 | STAT3 (0.65) | HSD17B2KMT2APKMUQCRBMAPT | |
| SCHEMBL6700596 | 0.80 | KMT2A (0.48) | HSD17B2KMT2APKMUQCRBMAPT | |
| SCHEMBL6699364 | 0.78 | HSD17B2 (0.54) | HSD17B2KMT2APKMUQCRBMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6693136-B1 | DISULFONAMIDE DERIVATIVES; PAIN, URINARY INCONTINENCE, BLADDER OVERACTIVITY | ABBOTT LABORATORIES | 2004-02-17 | — | — | US | disclosed |