SCHEMBL6743146

SCHEMBL6743146

N#CC1CCCC1O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18070918 1.00
SCHEMBL28525659 1.00
SCHEMBL8906433 1.00
SCHEMBL8906437 1.00
Cyanide SCHEMBL9274580 0.95 DPP4 (0.30)
Cyanide SCHEMBL9274569 0.95 DPP4 (0.30)
Cyanide SCHEMBL9274583 0.95 DPP4 (0.30)
SCHEMBL5511095 0.94
SCHEMBL2938716 0.94
SCHEMBL5511096 0.94

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11612606-B2 8-aminoisoquinoline compounds and uses thereof GENENTECH, INC. (US) 2023-03-28 US disclosed
EP-3860980-A1 8-AMINOISOQUINOLINE COMPOUNDS AND USES THEREOF F. Hoffmann-La Roche AG (CH) 2021-08-11 EP disclosed
US-20200108075-A1 8-AMINOISOQUINOLINE COMPOUNDS AND USES THEREOF GENENTECH, INC. (US) 2020-04-09 US disclosed
WO-2020072695-A1 8-AMINOISOQUINOLINE COMPOUNDS AND USES THEREOF GENENTECH, INC. (US) 2020-04-09 WO disclosed
US-6699695-B1 FOR EXAMPLE, CONVERTING 2-HYDROXY-4-METHYLTHIOBUTYRONITRILE INTO THE CORRESPONDING AMIDE, WHICH IS A PRECURSOR TO THE FEED SUPPLEMENT 2-HYDROXY-4-METHYLTHIOBUTYRIC ACID DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2004-03-02 US disclosed
EP-1055724-A1 MICROORGANISMS AND PROCESS FOR PRODUCING AMIDE COMPOUNDS Daicel Chemical Industries, Ltd. (JP) 2000-11-29 EP disclosed
US-5698526-A ANTICHOLESTEROL AGENT PFIZER INC. (US) 1997-12-16 US disclosed
EP-0737203-A1 STEROIDAL GLYCOSIDES PFIZER INC. (US) 1996-10-16 EP disclosed
WO-1995018144-A1 STEROIDAL GLYCOSIDES PFIZER INC. (US) 1995-07-06 WO disclosed
EP-0115054-B1 BETA-ELIMINATING POLYMERS FOR DIFFUSION CONTROL IN PHOTOGRAPHIC PRODUCTS POLAROID CORPORATION (US) 1988-02-10 EP disclosed
US-4631327-A β-Elimination polymers useful for providing diffusion control layers in diffusion transfer photographic products POLAROID CORPORATION (US) 1986-12-23 US disclosed
US-4522996-A ACRYLIC ESTER CARBAMATE CONTAINING LABILE PROTON POLAROID CORPORATION (US) 1985-06-11 US disclosed
EP-0115053-A2 Diffusion control layers in diffusion transfer photographic products POLAROID CORPORATION (US) 1984-08-08 EP disclosed
EP-0115054-A2 Beta-eliminating polymers for diffusion control in photographic products POLAROID CORPORATION (US) 1984-08-08 EP disclosed
US-4461824-A POLYMERS WHICH UNDERGO ELIMINATION IN ALKALINE ENVIRONMENT POLAROID CORPORATION (US) 1984-07-24 US disclosed
US-4458001-A HOLD-RELEASE LAYERS POLAROID CORPORATION (US) 1984-07-03 US disclosed
US-4010113-A TUNGSTEN OR MOLYBDENUM HALIDE- AN ALKYLALUMINUM HALIDE-ALCOHOL THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-03-01 US disclosed
US-3997471-A TUNGSTEN OR MOLYBDENUM HALIDE OR OXYHALIDE, AN ALKYLALUMINUM HALIDE, ALCOHOL THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-12-14 US disclosed
US-3945986-A RING OPENING POLYMERIZATION, TUNGSTEN OR MOLYBDENUM HALIDE, ALKYL ALUMINUM HALIDE, ALCOHOL CATALYST THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-03-23 US disclosed
US-3935179-A TUNGSTEN HALIDE OR OXYHALIDE, AN ALKYL-ALUMINUM HALIDE, ALCOHOL CATALYST THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-01-27 US disclosed